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1,2-Diacetoxylycorine

PubChem CID: 10429288

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Compound Synonyms 1,2-Diacetoxylycorine, 1,2-Diacetyllycorine, CHEMBL465295, LYCORINE DIACETATE, 1,2-Di-O-acetyllycorine, SCHEMBL12319317, BDBM50293602, PD179165, (1S,17S,18S,19S)-17-(acetyloxy)-5,7-dioxa-12-azapentacyclo[10.6.1.0^{2,10}.0^{4,8}.0^{15,19}]nonadeca-2,4(8),9,15-tetraen-18-yl acetate, (1S,2S,12bS,12cS)-1,2-Diol-2,4,5,7,12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diacetate
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 74.3
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3CC4CCC5CCCC(C3CC2C1)C54
Np Classifier Class Amarylidaceae alkaloids, Indolizidine alkaloids
Deep Smiles CC=O)O[C@@H][C@@H]OC=O)C)))C=C[C@@H][C@@H]6cccOCOc5cc9CN%13CC%16
Heavy Atom Count 27.0
Classyfire Class Amaryllidaceae alkaloids
Scaffold Graph Node Level C1CC2CCN3CC4CC5OCOC5CC4C(C1)C23
Classyfire Subclass Lycorine-type amaryllidaceae alkaloids
Isotope Atom Count 0.0
Molecular Complexity 677.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 4.0
Uniprot Id P08684, n.a.
Iupac Name [(1S,17S,18S,19S)-18-acetyloxy-5,7-dioxa-12-azapentacyclo[10.6.1.02,10.04,8.015,19]nonadeca-2,4(8),9,15-tetraen-17-yl] acetate
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Target Id NPT109
Xlogp 1.1
Gsk 4 400 Rule True
Molecular Formula C20H21NO6
Scaffold Graph Node Bond Level C1=C2CCN3Cc4cc5c(cc4C(CC1)C23)OCO5
Prediction Swissadme 1.0
Inchi Key LMZHAKUXAHOCST-VNTMZGSJSA-N
Silicos It Class Soluble
Fcsp3 0.5
Logs -2.954
Rotatable Bond Count 4.0
Logd 2.013
Synonyms 1,2-diacetyllycorine
Esol Class Soluble
Functional Groups CC(=O)OC, CC(C)=CC, CN(C)C, c1cOCO1
Compound Name 1,2-Diacetoxylycorine
Prediction Hob Swissadme 1.0
Exact Mass 371.137
Formal Charge 0.0
Monoisotopic Mass 371.137
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 371.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -2.754956244444446
Inchi InChI=1S/C20H21NO6/c1-10(22)26-17-5-12-3-4-21-8-13-6-15-16(25-9-24-15)7-14(13)18(19(12)21)20(17)27-11(2)23/h5-7,17-20H,3-4,8-9H2,1-2H3/t17-,18-,19+,20+/m0/s1
Smiles CC(=O)O[C@H]1C=C2CCN3[C@H]2[C@@H]([C@@H]1OC(=O)C)C4=CC5=C(C=C4C3)OCO5
Nring 5.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Lysine alkaloids, Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Crinum Lorifolium (Plant) Rel Props:Reference:ISBN:9788185042114
  • 2. Outgoing r'ship FOUND_IN to/from Lycoris Traubii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all