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(1R,13S,14Z,19S,21S)-14-(2-hydroxyethylidene)-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,11-tetraen-9-one

PubChem CID: 10382239

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 43.8
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CCC34C2CC1C1CCC(C)C(C2CCCCC23)C14
Np Classifier Class Strychnos type
Deep Smiles OC/C=CCNCC[C@@][C@@H]5C[C@@H]9C=CCC=O)N[C@H]%106)cc%11cccc6
Heavy Atom Count 25.0
Classyfire Class Strychnos alkaloids
Scaffold Graph Node Level CC1CN2CCC34C5CCCCC5N5C(O)CCC(C1CC23)C54
Isotope Atom Count 0.0
Molecular Complexity 698.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name (1R,13S,14Z,19S,21S)-14-(2-hydroxyethylidene)-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,11-tetraen-9-one
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 0.4
Gsk 4 400 Rule True
Molecular Formula C21H22N2O2
Scaffold Graph Node Bond Level C=C1CN2CCC34c5ccccc5N5C(=O)CC=C(C1CC23)C54
Inchi Key PNYOGGAOQVIZDM-KEUZPKPFSA-N
Silicos It Class Soluble
Rotatable Bond Count 1.0
Synonyms isostrychnine
Esol Class Soluble
Functional Groups C/C=C(C)C, CC=C(C)C, CN(C)C, CO, cN(C)C(C)=O
Compound Name (1R,13S,14Z,19S,21S)-14-(2-hydroxyethylidene)-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,11-tetraen-9-one
Exact Mass 334.168
Formal Charge 0.0
Monoisotopic Mass 334.168
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 334.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H22N2O2/c24-10-7-13-12-22-9-8-21-16-3-1-2-4-17(16)23-19(25)6-5-14(20(21)23)15(13)11-18(21)22/h1-5,7,15,18,20,24H,6,8-12H2/b13-7+/t15-,18-,20-,21+/m0/s1
Smiles C1CN2C/C(=C\CO)/[C@@H]3C[C@H]2[C@@]14[C@@H]5C3=CCC(=O)N5C6=CC=CC=C46
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Strychnos Ignatii (Plant) Rel Props:Reference:ISBN:9788172363093; ISBN:9788185042145