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Cryptophycin-29

PubChem CID: 10371754

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Compound Synonyms Cryptophycin 29, Cryptophycin-29, (3S,10R,13E,16S)-10-[(3-chloro-4-methoxyphenyl)methyl]-3-(2-methylpropyl)-16-[(E,2R)-4-phenylbut-3-en-2-yl]-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone, (3S,10R,13E,16S)-10-((3-chloro-4-methoxyphenyl)methyl)-3-(2-methylpropyl)-16-((2R,3E)-4-phenylbut-3-en-2-yl)-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone, (3S,10R,13E,16S)-10-((3-chloro-4-methoxyphenyl)methyl)-3-(2-methylpropyl)-16-((E,2R)-4-phenylbut-3-en-2-yl)-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone, (3S,10R,13E,16S)-10-[(3-chloro-4-methoxyphenyl)methyl]-3-(2-methylpropyl)-16-[(2R,3E)-4-phenylbut-3-en-2-yl]-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone, (3S,10R,13Z,16S)-10-((3-chloro-4-methoxyphenyl)methyl)-3-(2-methylpropyl)-16-((E,2R)-4-phenylbut-3-en-2-yl)-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone, (3S,10R,13Z,16S)-10-[(3-chloro-4-methoxyphenyl)methyl]-3-(2-methylpropyl)-16-[(E,2R)-4-phenylbut-3-en-2-yl]-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone, CHEBI:227840, DTXSID901307771
Prediction Swissadme 0.0
Topological Polar Surface Area 120.0
Hydrogen Bond Donor Count 2.0
Inchi Key XFXOMGLTDWTPTP-SEZBCZDQSA-N
Fcsp3 0.4117647058823529
Rotatable Bond Count 8.0
Heavy Atom Count 44.0
Compound Name Cryptophycin-29
Prediction Hob Swissadme 0.0
Exact Mass 624.26
Formal Charge 0.0
Monoisotopic Mass 624.26
Isotope Atom Count 0.0
Molecular Complexity 1010.0
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 625.1
Database Name cmaup_ingredients;pubchem
Covalent Unit Count 1.0
Defined Atom Stereocenter Count 4.0
Iupac Name (3S,10R,13E,16S)-10-[(3-chloro-4-methoxyphenyl)methyl]-3-(2-methylpropyl)-16-[(E,2R)-4-phenylbut-3-en-2-yl]-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 2.0
Prediction Hob 0.0
Esol -7.793522581818183
Inchi InChI=1S/C34H41ClN2O7/c1-22(2)19-30-34(41)44-28(23(3)13-14-24-9-6-5-7-10-24)11-8-12-31(38)37-27(33(40)36-18-17-32(39)43-30)21-25-15-16-29(42-4)26(35)20-25/h5-10,12-16,20,22-23,27-28,30H,11,17-19,21H2,1-4H3,(H,36,40)(H,37,38)/b12-8+,14-13+/t23-,27-,28+,30+/m1/s1
Smiles C[C@H](/C=C/C1=CC=CC=C1)[C@@H]2C/C=C/C(=O)N[C@@H](C(=O)NCCC(=O)O[C@H](C(=O)O2)CC(C)C)CC3=CC(=C(C=C3)OC)Cl
Xlogp 6.5
Defined Bond Stereocenter Count 2.0
Molecular Formula C34H41ClN2O7

  • 1. Outgoing r'ship FOUND_IN to/from Ajuga Nipponensis (Plant) Rel Props:Source_db:cmaup_ingredients
  • 2. Outgoing r'ship FOUND_IN to/from Eriobotrya Deflexa (Plant) Rel Props:Source_db:cmaup_ingredients
  • 3. Outgoing r'ship FOUND_IN to/from Grevillea Robusta (Plant) Rel Props:Source_db:cmaup_ingredients
  • 4. Outgoing r'ship FOUND_IN to/from Neurolaena Lobata (Plant) Rel Props:Source_db:cmaup_ingredients