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Napabucasin

PubChem CID: 10331844

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Compound Synonyms Napabucasin, 83280-65-3, 2-Acetylfuro-1,4-naphthoquinone, 2-acetylnaphtho[2,3-b]furan-4,9-dione, BBI608, 2-acetylbenzo[f][1]benzofuran-4,9-dione, BBI-608, 2-Acetyl-4H,9H-naphtho[2,3-b]furan-4,9-dione, 2-Acetylfuranonaphthoquinone, Z1HHM49K7O, BBI 608, 2-Acetylnaphtho(2,3-b)furan-4,9-dione, Napabucasin [USAN:INN], UNII-Z1HHM49K7O, Napabucasina, Napabucasine, FNQ, MFCD28155270, Napabucasin, BBI608, Napabucasin (BBI608), NAPABUCASIN [INN], NAPABUCASIN [JAN], NAPABUCASIN [USAN], Napabucasin (BBI608)?, NAPABUCASIN [WHO-DD], CHEMBL64130, Napabucasin (JAN/USAN/INN), SCHEMBL1883845, GTPL11358, DPHUWDIXHNQOSY-UHFFFAOYSA-N, BCP07628, EX-A1314, IDA28065, BDBM50366597, NSC788900, NSC816092, s7977, AKOS027470201, CCG-266871, CS-1747, DB12155, NSC-788900, NSC-816092, AC-32935, AS-60519, DA-65928, HY-13919, 2-Acetyl-naphtho[2,3-b]furan-4,9-dione, A3110, Cancer cell stemness inhibitor (Napabucasin), NS00070834, D10717, EN300-207428, F17379, BRD-K22064724-001-01-8, NAPHTHO(2,3-B)FURAN-4,9-DIONE, 2-ACETYL-, Q27294876, Z2027914355
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 64.4
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1C2CCCCC2C(C)C2CCCC12
Np Classifier Class Naphthoquinones
Deep Smiles CC=O)cccco5)C=O)ccC6=O))cccc6
Heavy Atom Count 18.0
Classyfire Class Naphthofurans
Scaffold Graph Node Level OC1C2CCCCC2C(O)C2OCCC12
Isotope Atom Count 0.0
Molecular Complexity 414.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id n.a., Q3B792, P16435, P40763, P0DTD1, P23458, O60674, P15559, Q96SW2
Iupac Name 2-acetylbenzo[f][1]benzofuran-4,9-dione
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Target Id NPT38
Xlogp 2.3
Gsk 4 400 Rule True
Molecular Formula C14H8O4
Scaffold Graph Node Bond Level O=C1c2ccccc2C(=O)c2occc21
Prediction Swissadme 0.0
Inchi Key DPHUWDIXHNQOSY-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.0714285714285714
Logs -4.084
Rotatable Bond Count 1.0
Logd 2.391
Synonyms 2-acetyl-naphtho(2,3-b)furan-4,9-dione, 2-acetyl-naphtho-[2,3-b] furan-4,9-dione, 2-acetylnaphthol[2,3-b]furan-4,9-dione
Esol Class Soluble
Functional Groups cC(C)=O, cC(c)=O, coc
Compound Name Napabucasin
Prediction Hob Swissadme 0.0
Exact Mass 240.042
Formal Charge 0.0
Monoisotopic Mass 240.042
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 240.21
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.151949022222222
Inchi InChI=1S/C14H8O4/c1-7(15)11-6-10-12(16)8-4-2-3-5-9(8)13(17)14(10)18-11/h2-6H,1H3
Smiles CC(=O)C1=CC2=C(O1)C(=O)C3=CC=CC=C3C2=O
Nring 3.0
Np Classifier Biosynthetic Pathway Polyketides
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Naphthalenes

  • 1. Outgoing r'ship FOUND_IN to/from Kigelia Africana (Plant) Rel Props:Reference:ISBN:9788172362461
  • 2. Outgoing r'ship FOUND_IN to/from Tabebuia Avellanedae (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Tabebuia Rosea (Plant) Rel Props:Reference:ISBN:9788172363093; ISBN:9788185042138