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3-[2-(1,1-Dimethyl-allyl)-6,7-bis-(3-methyl-but-2-enyl)-1H-indol-3-ylmethylene]-6-methyl-piperazine-2,5-dione

PubChem CID: 10321984

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Compound Synonyms Cristatin A, Cyclo-alanyl-6,7-disiopentenyl-2-(1\',1\'-dimethylallyl-8-(Z)-ene-tryptophan, (6Z)-3-methyl-6-[[2-(2-methylbut-3-en-2-yl)-6,7-bis(3-methylbut-2-enyl)-1H-indol-3-yl]methylidene]piperazine-2,5-dione, 3-[2-(1,1-Dimethyl-allyl)-6,7-bis-(3-methyl-but-2-enyl)-1H-indol-3-ylmethylene]-6-methyl-piperazine-2,5-dione, InChI=1/C29H37N3O2/c1-9-29(7,8)26-23(16-24-28(34)30-19(6)27(33)31-24)22-15-13-20(12-10-17(2)3)21(25(22)32-26)14-11-18(4)5/h9-11,13,15-16,19,32H,1,12,14H2,2-8H3,(H,30,34)(H,31,33)/b24-16
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 74.0
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC(C)C(CC2CCC3CCCCC32)C1
Np Classifier Class Indole diketopiperazine alkaloids (L-Trp, L-Ala)
Deep Smiles C=CCc[nH]ccc5/C=CNC=O)CNC6=O)))C)))))))cccc6CC=CC)C)))))CC=CC)C)))))))))))C)C
Heavy Atom Count 34.0
Classyfire Class Carboxylic acids and derivatives
Scaffold Graph Node Level OC1CNC(O)C(CC2CNC3CCCCC23)N1
Classyfire Subclass Amino acids, peptides, and analogues
Isotope Atom Count 0.0
Molecular Complexity 889.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name (6Z)-3-methyl-6-[[2-(2-methylbut-3-en-2-yl)-6,7-bis(3-methylbut-2-enyl)-1H-indol-3-yl]methylidene]piperazine-2,5-dione
Veber Rule True
Classyfire Superclass Organic acids and derivatives
Xlogp 7.2
Gsk 4 400 Rule False
Molecular Formula C29H37N3O2
Scaffold Graph Node Bond Level O=C1CNC(=O)C(=Cc2c[nH]c3ccccc23)N1
Inchi Key RERRWNNFPWXUTC-JLPGSUDCSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 7.0
Synonyms cristatin a
Esol Class Poorly soluble
Functional Groups C=CC, CC=C(C)C, c/C=C1NC(=O)CNC1=O, c[nH]c
Compound Name 3-[2-(1,1-Dimethyl-allyl)-6,7-bis-(3-methyl-but-2-enyl)-1H-indol-3-ylmethylene]-6-methyl-piperazine-2,5-dione
Exact Mass 459.289
Formal Charge 0.0
Monoisotopic Mass 459.289
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 459.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C29H37N3O2/c1-9-29(7,8)26-23(16-24-28(34)30-19(6)27(33)31-24)22-15-13-20(12-10-17(2)3)21(25(22)32-26)14-11-18(4)5/h9-11,13,15-16,19,32H,1,12,14H2,2-8H3,(H,30,34)(H,31,33)/b24-16-
Smiles CC1C(=O)N/C(=C\C2=C(NC3=C2C=CC(=C3CC=C(C)C)CC=C(C)C)C(C)(C)C=C)/C(=O)N1
Np Classifier Biosynthetic Pathway Alkaloids, Amino acids and Peptides
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Peptide alkaloids