Thymoquinone
PubChem CID: 10281
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| Compound Synonyms | Thymoquinone, 490-91-5, Thymoquinon, p-Cymene-2,5-dione, 2-Isopropyl-5-methyl-1,4-benzoquinone, p-Mentha-3,6-diene-2,5-dione, 2,5-CYCLOHEXADIENE-1,4-DIONE, 2-METHYL-5-(1-METHYLETHYL)-, 2-Isopropyl-5-methylbenzoquinone, 2-Isopropyl-5-methylcyclohexa-2,5-diene-1,4-dione, 2-Isopropyl-5-methyl-p-benzoquinone, 5-Isopropyl-2-methyl-1,4-benzoquinone, 2-methyl-5-propan-2-ylcyclohexa-2,5-diene-1,4-dione, 2-Isopropyl-5-methylbenzo-1,4-quinone, NSC 2228, 2-Methyl-5-isopropyl-p-benzoquinone, CCRIS 7152, NSC-2228, EINECS 207-721-1, O60IE26NUF, 2-methyl-5-(propan-2-yl)cyclohexa-2,5-diene-1,4-dione, BRN 1939047, AI3-17758, NSC2228, 2,5-Cyclohexadiene-1,4-dione, 5-isopropyl-2-methyl-, MFCD00001602, UNII-O60IE26NUF, 2-Methyl-5-isopropyl-1,4-benzoquinone, 2-Methyl-5-(1-methylethyl)-2,5-cyclohexadiene-1,4-dione, CHEBI:113532, 5-Isopropyl-2-methyl-p-benzoquinone, 5-Isopropyl-2-methyl-2,5-Cyclohexadiene-1,4-dione, thymolquinone, Thymoil, 4hco, p-Mentha-3,5-dione, Spectrum_001237, Thymoquinone (Standard), SpecPlus_000457, Thymoquinone, >=98%, Spectrum2_000700, Spectrum3_001345, Spectrum4_001895, Spectrum5_000550, BSPBio_003129, KBioGR_002455, KBioSS_001717, DivK1c_006553, SCHEMBL542535, THYMOQUINONE [WHO-DD], SPBio_000859, CHEMBL1672002, DTXSID9060079, HY-D0803R, KBio1_001497, KBio2_001717, KBio2_004285, KBio2_006853, KBio3_002349, Thymoquinone, analytical standard, 2-Methyl-5-iso-propylbenzoquinone, BDBM166686, BCP16946, HY-D0803, WLN: L6V DVJ B1 EY1&1, 2,4-dione, 5-isopropyl-2-methyl-, CCG-40027, s4761, AKOS003368628, FT09858, NCGC00178250-01, NCGC00178250-05, AS-11327, DA-68178, p-Mentha-3,6-diene-2,5-dione (8CI), 2-Isopropyl-5-methylbenzo-1,4-quinone #, 2,4-dione, 2-methyl-5-(1-methylethyl)-, CS-0012226, NS00031853, T0795, EN300-264364, T72517, SR-05000002192, Q7799650, SR-05000002192-2, BRD-K97566842-001-03-5, Thymoquinone, 2-isopropyl-5-methylbenzo-1,4-quinone, Z1255372388, 2-methyl-5-(propan-2-yl)cyclohexa-2,5-diene-1,4-dione (F8), 2-Methyl-5-(1-methylethyl)-2,5-cyclohexadiene-1,4-dione, 9CI, InChI=1/C10H12O2/c1-6(2)8-5-9(11)7(3)4-10(8)12/h4-6H,1-3H, 207-721-1 |
|---|---|
| Ghose Rule | True |
| Classyfire Kingdom | Organic compounds |
| Topological Polar Surface Area | 34.1 |
| Hydrogen Bond Donor Count | 0.0 |
| Pfizer 3 75 Rule | False |
| Scaffold Graph Level | CC1CCC(C)CC1 |
| Deep Smiles | CCC=CC=O)C=CC6=O)))C)))))C |
| Heavy Atom Count | 12.0 |
| Classyfire Class | Organooxygen compounds |
| Description | Major constituent of seed oil of black cumin, Nigella sativa (24%). Thymoquinone is found in herbs and spices and winter savory. |
| Scaffold Graph Node Level | OC1CCC(O)CC1 |
| Classyfire Subclass | Carbonyl compounds |
| Isotope Atom Count | 0.0 |
| Molecular Complexity | 293.0 |
| Database Name | cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem |
| Defined Atom Stereocenter Count | 0.0 |
| Uniprot Id | n.a., O42275, P81908, Q9NPD5, Q9Y6L6, P10845, P53350, Q9NYY3, Q9H4B4 |
| Iupac Name | 2-methyl-5-propan-2-ylcyclohexa-2,5-diene-1,4-dione |
| Prediction Hob | 1.0 |
| Class | Organooxygen compounds |
| Veber Rule | True |
| Classyfire Superclass | Organic oxygen compounds |
| Target Id | NPT831, NPT3414 |
| Xlogp | 2.0 |
| Superclass | Organic oxygen compounds |
| Subclass | Carbonyl compounds |
| Gsk 4 400 Rule | True |
| Molecular Formula | C10H12O2 |
| Scaffold Graph Node Bond Level | O=C1C=CC(=O)C=C1 |
| Prediction Swissadme | 1.0 |
| Inchi Key | KEQHJBNSCLWCAE-UHFFFAOYSA-N |
| Silicos It Class | Soluble |
| Fcsp3 | 0.4 |
| Logs | -2.367 |
| Rotatable Bond Count | 1.0 |
| State | Solid |
| Logd | 2.835 |
| Synonyms | 2-Isopropyl-5-methyl-1,4-benzoquinone, 2-Isopropyl-5-methyl-p-benzoquinone, 2-Isopropyl-5-methylbenzo-1,4-quinone, 2-Isopropyl-5-methylbenzoquinone, 2-Methyl-5-(1-methylethyl)-2,5-cyclohexadiene-1,4-dione, 2-Methyl-5-(1-methylethyl)-2,5-cyclohexadiene-1,4-dione, 9CI, 2-Methyl-5-isopropyl-1,4-benzoquinone, 2-Methyl-5-isopropyl-p-benzoquinone, 2,5-Cyclohexadiene-1,4-dione, 2-methyl-5-(1-methylethyl)-, 2,5-Cyclohexadiene-1,4-dione, 5-isopropyl-2-methyl-, 5-Isopropyl-2-methyl-1,4-benzoquinone, 5-Isopropyl-2-methyl-2,5-cyclohexadiene-1,4-dione, 5-Isopropyl-2-methyl-p-benzoquinone, p-Cymene-2,5-dione, p-Mentha-3,6-diene-2,5-dione (8CI), Polythymoquinone, Thymoil, Thymolquinone, Thymoquinon, Thymoquinone, p-Mentha-3,6-diene-2,5-dione, TQ, 2-Methyl-5-(1-methylethyl)-2,5-cyclohexadiene-1,4-dione, 9ci, 2-Methyl-5-isopropyl-P-benzoquinone, 5-Isopropyl-2-methyl-P-benzoquinone, P-Mentha-3,6-diene-2,5-dione (8ci), Dihydrothymoquinone, th ymoquinone, thymoquinone |
| Esol Class | Soluble |
| Functional Groups | CC1=CC(=O)C(C)=CC1=O |
| Compound Name | Thymoquinone |
| Kingdom | Organic compounds |
| Prediction Hob Swissadme | 1.0 |
| Exact Mass | 164.084 |
| Formal Charge | 0.0 |
| Monoisotopic Mass | 164.084 |
| Hydrogen Bond Acceptor Count | 2.0 |
| Molecular Weight | 164.2 |
| Gi Absorption | True |
| Covalent Unit Count | 1.0 |
| Total Atom Stereocenter Count | 0.0 |
| Total Bond Stereocenter Count | 0.0 |
| Molecular Framework | Aliphatic homomonocyclic compounds |
| Lipinski Rule Of 5 | True |
| Esol | -2.1780648 |
| Inchi | InChI=1S/C10H12O2/c1-6(2)8-5-9(11)7(3)4-10(8)12/h4-6H,1-3H3 |
| Smiles | CC1=CC(=O)C(=CC1=O)C(C)C |
| Nring | 1.0 |
| Np Classifier Biosynthetic Pathway | Terpenoids |
| Defined Bond Stereocenter Count | 0.0 |
| Egan Rule | True |
| Taxonomy Direct Parent | P-benzoquinones |
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FOUND_INto/from Polygala Sibirica (Plant) Rel Props:Reference: - 159. Outgoing r'ship
FOUND_INto/from Polygala Telephioides (Plant) Rel Props:Reference: - 160. Outgoing r'ship
FOUND_INto/from Polygala Tenuifolia (Plant) Rel Props:Reference: - 161. Outgoing r'ship
FOUND_INto/from Polygala Vulgaris (Plant) Rel Props:Reference: - 162. Outgoing r'ship
FOUND_INto/from Prunella Vulgaris (Plant) Rel Props:Reference: - 163. Outgoing r'ship
FOUND_INto/from Pueraria Montana (Plant) Rel Props:Reference: - 164. Outgoing r'ship
FOUND_INto/from Pulmonaria Mollis (Plant) Rel Props:Reference: - 165. Outgoing r'ship
FOUND_INto/from Pyracantha Coccinea (Plant) Rel Props:Reference: - 166. Outgoing r'ship
FOUND_INto/from Pyracantha Crenulata (Plant) Rel Props:Reference: - 167. Outgoing r'ship
FOUND_INto/from Quamoclit Vulgaris (Plant) Rel Props:Reference: - 168. Outgoing r'ship
FOUND_INto/from Rhododendron Luteum (Plant) Rel Props:Reference: - 169. Outgoing r'ship
FOUND_INto/from Rhus Vulgaris (Plant) Rel Props:Reference: - 170. Outgoing r'ship
FOUND_INto/from Rosmarinus Officinalis (Plant) Rel Props:Reference:https://doi.org/10.1080/0972-060x.2003.10643331 - 171. Outgoing r'ship
FOUND_INto/from Ruta Montana (Plant) Rel Props:Reference: - 172. Outgoing r'ship
FOUND_INto/from Satureja Atropatana (Plant) Rel Props:Reference: - 173. Outgoing r'ship
FOUND_INto/from Satureja Cuneifolia (Plant) Rel Props:Reference: - 174. Outgoing r'ship
FOUND_INto/from Satureja Hortensis (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.2068 - 175. Outgoing r'ship
FOUND_INto/from Satureja Montana (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all;npass_chem_all - 176. Outgoing r'ship
FOUND_INto/from Satureja Odora (Plant) Rel Props:Reference: - 177. Outgoing r'ship
FOUND_INto/from Satureja Thymbra (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.1489 - 178. Outgoing r'ship
FOUND_INto/from Satureja Vulgaris (Plant) Rel Props:Reference: - 179. Outgoing r'ship
FOUND_INto/from Senecio Vulgaris (Plant) Rel Props:Reference: - 180. Outgoing r'ship
FOUND_INto/from Senna Montana (Plant) Rel Props:Reference: - 181. Outgoing r'ship
FOUND_INto/from Silene Vulgaris (Plant) Rel Props:Reference: - 182. Outgoing r'ship
FOUND_INto/from Sophora Mollis (Plant) Rel Props:Reference: - 183. Outgoing r'ship
FOUND_INto/from Stephania Glandulifera (Plant) Rel Props:Reference: - 184. Outgoing r'ship
FOUND_INto/from Syringa Vulgaris (Plant) Rel Props:Reference: - 185. Outgoing r'ship
FOUND_INto/from Tamarix Dioica (Plant) Rel Props:Reference: - 186. Outgoing r'ship
FOUND_INto/from Teramnus Mollis (Plant) Rel Props:Reference: - 187. Outgoing r'ship
FOUND_INto/from Tetraclinis Articulata (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2005.9698865 - 188. Outgoing r'ship
FOUND_INto/from Teucrium Alyssifolium (Plant) Rel Props:Reference: - 189. Outgoing r'ship
FOUND_INto/from Teucrium Asiaticum (Plant) Rel Props:Reference: - 190. Outgoing r'ship
FOUND_INto/from Teucrium Betonicum (Plant) Rel Props:Reference: - 191. Outgoing r'ship
FOUND_INto/from Teucrium Bidentatum (Plant) Rel Props:Reference: - 192. Outgoing r'ship
FOUND_INto/from Teucrium Chamaedrys (Plant) Rel Props:Reference: - 193. Outgoing r'ship
FOUND_INto/from Teucrium Cossonii (Plant) Rel Props:Reference: - 194. Outgoing r'ship
FOUND_INto/from Teucrium Depressum (Plant) Rel Props:Reference: - 195. Outgoing r'ship
FOUND_INto/from Teucrium Fragile (Plant) Rel Props:Reference: - 196. Outgoing r'ship
FOUND_INto/from Teucrium Fruticans (Plant) Rel Props:Reference: - 197. Outgoing r'ship
FOUND_INto/from Teucrium Heterophyllum (Plant) Rel Props:Reference: - 198. Outgoing r'ship
FOUND_INto/from Teucrium Lanigerum (Plant) Rel Props:Reference: - 199. Outgoing r'ship
FOUND_INto/from Teucrium Leucocladum (Plant) Rel Props:Reference: - 200. Outgoing r'ship
FOUND_INto/from Teucrium Marum (Plant) Rel Props:Reference: - 201. Outgoing r'ship
FOUND_INto/from Teucrium Montanum (Plant) Rel Props:Reference: - 202. Outgoing r'ship
FOUND_INto/from Teucrium Nuchense (Plant) Rel Props:Reference: - 203. Outgoing r'ship
FOUND_INto/from Teucrium Orientale (Plant) Rel Props:Reference: - 204. Outgoing r'ship
FOUND_INto/from Teucrium Oxylepis (Plant) Rel Props:Reference: - 205. Outgoing r'ship
FOUND_INto/from Teucrium Pernyi (Plant) Rel Props:Reference: - 206. Outgoing r'ship
FOUND_INto/from Teucrium Pestalozzae (Plant) Rel Props:Reference: - 207. Outgoing r'ship
FOUND_INto/from Teucrium Pilosum (Plant) Rel Props:Reference: - 208. Outgoing r'ship
FOUND_INto/from Teucrium Polium (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2014.935065 - 209. Outgoing r'ship
FOUND_INto/from Teucrium Quadrifarium (Plant) Rel Props:Reference: - 210. Outgoing r'ship
FOUND_INto/from Teucrium Scordium (Plant) Rel Props:Reference: - 211. Outgoing r'ship
FOUND_INto/from Teucrium Scorodonia (Plant) Rel Props:Reference: - 212. Outgoing r'ship
FOUND_INto/from Teucrium Viscidum (Plant) Rel Props:Reference: - 213. Outgoing r'ship
FOUND_INto/from Teucrium Yemense (Plant) Rel Props:Reference: - 214. Outgoing r'ship
FOUND_INto/from Thermopsis Mollis (Plant) Rel Props:Reference: - 215. Outgoing r'ship
FOUND_INto/from Thymbra Capitata (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.1489 - 216. Outgoing r'ship
FOUND_INto/from Thymus Fedtschenkoi (Plant) Rel Props:Reference: - 217. Outgoing r'ship
FOUND_INto/from Thymus Kotschyanus (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2013.764159 - 218. Outgoing r'ship
FOUND_INto/from Thymus Linearis (Plant) Rel Props:Reference: - 219. Outgoing r'ship
FOUND_INto/from Thymus Magnus (Plant) Rel Props:Reference: - 220. Outgoing r'ship
FOUND_INto/from Thymus Migricus (Plant) Rel Props:Reference: - 221. Outgoing r'ship
FOUND_INto/from Thymus Piperella (Plant) Rel Props:Reference: - 222. Outgoing r'ship
FOUND_INto/from Thymus Praecox (Plant) Rel Props:Reference: - 223. Outgoing r'ship
FOUND_INto/from Thymus Pulegioides (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2012.10644041 - 224. Outgoing r'ship
FOUND_INto/from Thymus Quinquecostatus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 225. Outgoing r'ship
FOUND_INto/from Thymus Serpyllum (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.2068 - 226. Outgoing r'ship
FOUND_INto/from Thymus Transcaucasicus (Plant) Rel Props:Reference: - 227. Outgoing r'ship
FOUND_INto/from Thymus Vulgaris (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 228. Outgoing r'ship
FOUND_INto/from Tilia Vulgaris (Plant) Rel Props:Reference: - 229. Outgoing r'ship
FOUND_INto/from Trichosanthes Dioica (Plant) Rel Props:Reference: - 230. Outgoing r'ship
FOUND_INto/from Urtica Dioica (Plant) Rel Props:Reference: - 231. Outgoing r'ship
FOUND_INto/from Utricularia Vulgaris (Plant) Rel Props:Reference: - 232. Outgoing r'ship
FOUND_INto/from Vernicia Montana (Plant) Rel Props:Reference: - 233. Outgoing r'ship
FOUND_INto/from Vernonia Esculenta (Plant) Rel Props:Reference: - 234. Outgoing r'ship
FOUND_INto/from Wyethia Mollis (Plant) Rel Props:Reference: - 235. Outgoing r'ship
FOUND_INto/from Zanthoxylum Fagara (Plant) Rel Props:Reference: - 236. Outgoing r'ship
FOUND_INto/from Zizyphus Vulgaris (Plant) Rel Props:Reference: