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(2S)-2-(dimethylamino)-N-[(2S,3S)-1-[(13S,16Z)-19-methoxy-8,14-dioxo-2-oxa-6,9,15-triazatetracyclo[16.3.1.03,7.09,13]docosa-1(22),16,18,20-tetraen-6-yl]-3-methyl-1-oxopentan-2-yl]-3-phenylpropanamide

PubChem CID: 102469280

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Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 121.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC(CCC1CCCCC1)CCC(C)C1CCC2CC3CCCC(CCCC(C)C4CCCC4C(C)C21)C3
Np Classifier Class Ansa peptide alkaloids
Deep Smiles CC[C@@H][C@@H]C=O)NCCCC5C=O)NCCC[C@H]5C=O)N/C=C/cccO%16)ccc6OC))))))))))))))))))))))))NC=O)[C@@H]NC)C))Ccccccc6)))))))))))C
Heavy Atom Count 47.0
Classyfire Class Carboxylic acids and derivatives
Scaffold Graph Node Level OC(CCC1CCCCC1)NCC(O)N1CCC2OC3CCCC(CCNC(O)C4CCCN4C(O)C21)C3
Classyfire Subclass Amino acids, peptides, and analogues
Isotope Atom Count 0.0
Molecular Complexity 1140.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name (2S)-2-(dimethylamino)-N-[(2S,3S)-1-[(13S,16Z)-19-methoxy-8,14-dioxo-2-oxa-6,9,15-triazatetracyclo[16.3.1.03,7.09,13]docosa-1(22),16,18,20-tetraen-6-yl]-3-methyl-1-oxopentan-2-yl]-3-phenylpropanamide
Veber Rule True
Classyfire Superclass Organic acids and derivatives
Xlogp 4.3
Gsk 4 400 Rule False
Molecular Formula C36H47N5O6
Scaffold Graph Node Bond Level O=C(CCc1ccccc1)NCC(=O)N1CCC2Oc3cccc(c3)C=CNC(=O)C3CCCN3C(=O)C21
Inchi Key ASDABTDBYCJZRI-GJQVRCCMSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 9.0
Synonyms zizyphine c
Esol Class Moderately soluble
Functional Groups CC(=O)N(C)C, CN(C)C, CN(C)C(C)=O, CNC(C)=O, c/C=C/NC(C)=O, cOC
Compound Name (2S)-2-(dimethylamino)-N-[(2S,3S)-1-[(13S,16Z)-19-methoxy-8,14-dioxo-2-oxa-6,9,15-triazatetracyclo[16.3.1.03,7.09,13]docosa-1(22),16,18,20-tetraen-6-yl]-3-methyl-1-oxopentan-2-yl]-3-phenylpropanamide
Exact Mass 645.353
Formal Charge 0.0
Monoisotopic Mass 645.353
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 645.8
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C36H47N5O6/c1-6-23(2)31(38-34(43)28(39(3)4)21-24-11-8-7-9-12-24)35(44)41-20-17-30-32(41)36(45)40-19-10-13-27(40)33(42)37-18-16-25-22-26(47-30)14-15-29(25)46-5/h7-9,11-12,14-16,18,22-23,27-28,30-32H,6,10,13,17,19-21H2,1-5H3,(H,37,42)(H,38,43)/b18-16-/t23-,27-,28-,30?,31-,32?/m0/s1
Smiles CC[C@H](C)[C@@H](C(=O)N1CCC2C1C(=O)N3CCC[C@H]3C(=O)N/C=C\C4=C(C=CC(=C4)O2)OC)NC(=O)[C@H](CC5=CC=CC=C5)N(C)C
Np Classifier Biosynthetic Pathway Alkaloids, Amino acids and Peptides
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Peptide alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Ziziphus Oenopolia (Plant) Rel Props:Reference:ISBN:9780387706375