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[(1R,9R,10S,12R,13S,14R,16S,17R,18R)-4-acetyl-13-ethyl-14-hydroxy-8-methyl-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2(7),3,5-trien-18-yl] acetate

PubChem CID: 102278633

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 70.1
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1C3CC4CCC3C3CC21CC43
Np Classifier Class Corynanthe type
Deep Smiles CC[C@H][C@@H]C[C@@H]N[C@@H]6O))[C@@H][C@@H]6[C@@H]OC=O)C)))[C@][C@H]7NC)cc5cccc6))C=O)C))))))))C5
Heavy Atom Count 30.0
Classyfire Class Ajmaline-sarpagine alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1C3CC4CCN3C3CC21CC43
Isotope Atom Count 0.0
Molecular Complexity 787.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 9.0
Iupac Name [(1R,9R,10S,12R,13S,14R,16S,17R,18R)-4-acetyl-13-ethyl-14-hydroxy-8-methyl-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2(7),3,5-trien-18-yl] acetate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.1
Gsk 4 400 Rule False
Molecular Formula C24H30N2O4
Scaffold Graph Node Bond Level c1ccc2c(c1)NC1C3CC4CCN3C3CC21CC43
Inchi Key HCAKSQLCJKRVQI-SJXKWLFXSA-N
Silicos It Class Soluble
Rotatable Bond Count 4.0
Synonyms ajmalinimine
Esol Class Moderately soluble
Functional Groups CC(=O)OC, C[C@@H](O)N(C)C, cC(C)=O, cN(C)C
Compound Name [(1R,9R,10S,12R,13S,14R,16S,17R,18R)-4-acetyl-13-ethyl-14-hydroxy-8-methyl-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2(7),3,5-trien-18-yl] acetate
Exact Mass 410.221
Formal Charge 0.0
Monoisotopic Mass 410.221
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 410.5
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C24H30N2O4/c1-5-14-15-9-18-21-24(16-8-13(11(2)27)6-7-17(16)25(21)4)10-19(26(18)23(14)29)20(15)22(24)30-12(3)28/h6-8,14-15,18-23,29H,5,9-10H2,1-4H3/t14-,15-,18-,19-,20+,21-,22+,23+,24+/m0/s1
Smiles CC[C@H]1[C@@H]2C[C@H]3[C@H]4[C@@]5(C[C@@H]([C@@H]2[C@H]5OC(=O)C)N3[C@@H]1O)C6=C(N4C)C=CC(=C6)C(=O)C
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Rauvolfia Serpentina (Plant) Rel Props:Reference:https://doi.org/10.1186/s12906-015-0683-7