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(9R,12R,13S,14R,16S,17S,18R)-13-ethyl-8-methyl-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2(7),3,5-triene-6,14,18-triol

PubChem CID: 102271366

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 67.2
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1C3CC4CCC3C3CC21CC43
Np Classifier Class Corynanthe type
Deep Smiles CC[C@H][C@@H]CCN[C@@H]6O))[C@@H][C@H]6[C@@H]O)C[C@H]7NC)cc5cccc6O)))))))))C5
Heavy Atom Count 25.0
Classyfire Class Ajmaline-sarpagine alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1C3CC4CCN3C3CC21CC43
Isotope Atom Count 0.0
Molecular Complexity 601.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 7.0
Iupac Name (9R,12R,13S,14R,16S,17S,18R)-13-ethyl-8-methyl-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2(7),3,5-triene-6,14,18-triol
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.5
Gsk 4 400 Rule True
Molecular Formula C20H26N2O3
Scaffold Graph Node Bond Level c1ccc2c(c1)NC1C3CC4CCN3C3CC21CC43
Inchi Key RAGDTPVHROXSDN-KHDRFSGKSA-N
Silicos It Class Soluble
Rotatable Bond Count 1.0
Synonyms 12-hydroxyajmaline
Esol Class Soluble
Functional Groups CN(C)[C@@H](C)O, CO, cN(C)C, cO
Compound Name (9R,12R,13S,14R,16S,17S,18R)-13-ethyl-8-methyl-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2(7),3,5-triene-6,14,18-triol
Exact Mass 342.194
Formal Charge 0.0
Monoisotopic Mass 342.194
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 342.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C20H26N2O3/c1-3-9-10-7-12-17-20(11-5-4-6-14(23)16(11)21(17)2)8-13(15(10)18(20)24)22(12)19(9)25/h4-6,9-10,12-13,15,17-19,23-25H,3,7-8H2,1-2H3/t9-,10-,12?,13-,15-,17-,18+,19+,20?/m0/s1
Smiles CC[C@H]1[C@@H]2CC3[C@H]4C5(C[C@@H]([C@H]2[C@H]5O)N3[C@@H]1O)C6=C(N4C)C(=CC=C6)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Rauvolfia Serpentina (Plant) Rel Props:Reference:ISBN:9788185042145