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(7S,8R)-6'-methylspiro[6,8-dihydrocyclopenta[g][1,3]benzodioxole-7,5'-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinoline]-8-ol

PubChem CID: 102118431

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 60.4
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3CCCC4(CC5CCC6CCCC6C5C4)C3CC2C1
Np Classifier Class Isoquinoline alkaloids
Deep Smiles CNCCcc[C@]6Ccc[C@H]5O))cOCOc5cc9)))))))))))cccc6)OCO5
Heavy Atom Count 26.0
Classyfire Class Tetrahydroisoquinolines
Scaffold Graph Node Level C1CC2CC3OCOC3CC2C2(CC3CCC4OCOC4C3C2)N1
Isotope Atom Count 0.0
Molecular Complexity 574.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name (7S,8R)-6'-methylspiro[6,8-dihydrocyclopenta[g][1,3]benzodioxole-7,5'-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinoline]-8-ol
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 2.2
Gsk 4 400 Rule True
Molecular Formula C20H19NO5
Scaffold Graph Node Bond Level c1cc2c(c3c1CC1(C3)NCCc3cc4c(cc31)OCO4)OCO2
Inchi Key AKCAVBOVRWGORC-UXHICEINSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 0.0
Synonyms dihydrofumariline
Esol Class Soluble
Functional Groups CN(C)C, CO, c1cOCO1
Compound Name (7S,8R)-6'-methylspiro[6,8-dihydrocyclopenta[g][1,3]benzodioxole-7,5'-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinoline]-8-ol
Exact Mass 353.126
Formal Charge 0.0
Monoisotopic Mass 353.126
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 353.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C20H19NO5/c1-21-5-4-11-6-15-16(25-9-24-15)7-13(11)20(21)8-12-2-3-14-18(26-10-23-14)17(12)19(20)22/h2-3,6-7,19,22H,4-5,8-10H2,1H3/t19-,20+/m1/s1
Smiles CN1CCC2=CC3=C(C=C2[C@]14CC5=C([C@H]4O)C6=C(C=C5)OCO6)OCO3
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

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