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methyl (1R,12R,19R)-5-methoxy-12-[(1R)-1-(7-methoxy-1,3-benzodioxole-5-carbonyl)oxyethyl]-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,9-tetraene-10-carboxylate

PubChem CID: 102117082

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Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 105.0
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CCC12CCCC3CCC4(C(CC1)CC1CCCCC14)C32)C1CCC2CCCC2C1
Np Classifier Class Aspidosperma type
Deep Smiles COcccccc6)NC=CC[C@][C@H][C@@]96CCN5CCC9))))))))[C@H]OC=O)cccOC))ccc6)OCO5))))))))))C))))C=O)OC
Heavy Atom Count 41.0
Classyfire Class Aspidospermatan-type alkaloids
Scaffold Graph Node Level OC(OCC12CCCN3CCC4(C(CC1)NC1CCCCC14)C32)C1CCC2OCOC2C1
Isotope Atom Count 0.0
Molecular Complexity 1100.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name methyl (1R,12R,19R)-5-methoxy-12-[(1R)-1-(7-methoxy-1,3-benzodioxole-5-carbonyl)oxyethyl]-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,9-tetraene-10-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 4.3
Gsk 4 400 Rule False
Molecular Formula C31H34N2O8
Scaffold Graph Node Bond Level O=C(OCC12CC=C3Nc4ccccc4C34CCN(CCC1)C24)c1ccc2c(c1)OCO2
Inchi Key ZVLITPGUZVSYOS-OOBHTYFASA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 8.0
Synonyms echitoserpine
Esol Class Moderately soluble
Functional Groups CN(C)C, c1cOCO1, cC(=O)OC, cNC(C)=C(C)C(=O)OC, cOC
Compound Name methyl (1R,12R,19R)-5-methoxy-12-[(1R)-1-(7-methoxy-1,3-benzodioxole-5-carbonyl)oxyethyl]-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,9-tetraene-10-carboxylate
Exact Mass 562.232
Formal Charge 0.0
Monoisotopic Mass 562.232
Hydrogen Bond Acceptor Count 10.0
Molecular Weight 562.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C31H34N2O8/c1-17(41-27(34)18-12-23(37-3)25-24(13-18)39-16-40-25)30-8-5-10-33-11-9-31(29(30)33)21-7-6-19(36-2)14-22(21)32-26(31)20(15-30)28(35)38-4/h6-7,12-14,17,29,32H,5,8-11,15-16H2,1-4H3/t17-,29+,30+,31+/m1/s1
Smiles C[C@H]([C@@]12CCCN3[C@@H]1[C@@]4(CC3)C5=C(C=C(C=C5)OC)NC4=C(C2)C(=O)OC)OC(=O)C6=CC7=C(C(=C6)OC)OCO7
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Alstonia Venenata (Plant) Rel Props:Reference:ISBN:9770972795006; ISBN:9788172360481; ISBN:9788185042084