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methyl (1R,12R,19R)-12-[(1R)-1-acetyloxyethyl]-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,9-tetraene-10-carboxylate

PubChem CID: 102090470

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 77.1
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule True
Scaffold Graph Level C1CCC2C(C1)CC1CCC3CCCC4CCC12C34
Np Classifier Class Aspidosperma type
Deep Smiles COC=O)C=CNcc[C@]5[C@@H][C@]C9)CCCN6CC9))))))[C@H]OC=O)C)))C)))))cccc6)OC
Heavy Atom Count 31.0
Classyfire Class Aspidospermatan-type alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1CCC3CCCN4CCC12C34
Isotope Atom Count 0.0
Molecular Complexity 812.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name methyl (1R,12R,19R)-12-[(1R)-1-acetyloxyethyl]-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,9-tetraene-10-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.9
Gsk 4 400 Rule False
Molecular Formula C24H30N2O5
Scaffold Graph Node Bond Level C1=C2Nc3ccccc3C23CCN2CCCC(C1)C23
Inchi Key WQLDCBFCPROBTH-SELBWQTGSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 6.0
Synonyms echitovenaldine
Esol Class Moderately soluble
Functional Groups CC(=O)OC, CN(C)C, cNC(C)=C(C)C(=O)OC, cOC
Compound Name methyl (1R,12R,19R)-12-[(1R)-1-acetyloxyethyl]-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,9-tetraene-10-carboxylate
Exact Mass 426.215
Formal Charge 0.0
Monoisotopic Mass 426.215
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 426.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C24H30N2O5/c1-14(31-15(2)27)23-8-5-10-26-11-9-24(22(23)26)18-7-6-16(29-3)12-19(18)25-20(24)17(13-23)21(28)30-4/h6-7,12,14,22,25H,5,8-11,13H2,1-4H3/t14-,22+,23+,24+/m1/s1
Smiles C[C@H]([C@@]12CCCN3[C@@H]1[C@@]4(CC3)C5=C(C=C(C=C5)OC)NC4=C(C2)C(=O)OC)OC(=O)C
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Alstonia Venenata (Plant) Rel Props:Reference:ISBN:9770972795006; ISBN:9788172360481; ISBN:9788185042084