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(1R,6S,14S,15S,18S,20S,23R,24S)-20-hydroxy-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacos-2(11)-en-17-one

PubChem CID: 102067555

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Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 40.5
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2C(CC3C4CC5CCCCC5CC4CCC32)C2CCCCC12
Np Classifier Class Steroidal alkaloids, Terpenoid alkaloids
Deep Smiles O[C@H]CC[C@][C@H]C6)C=O)C[C@@H][C@@H]6C[C@@H][C@H]5CCC=C6CNC[C@@H]C)CCC6C%10C)))))))))))))))))))))C
Heavy Atom Count 30.0
Classyfire Class Piperidines
Scaffold Graph Node Level OC1CC2C(CC3C4CN5CCCCC5CC4CCC32)C2CCCCC12
Isotope Atom Count 0.0
Molecular Complexity 773.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 8.0
Iupac Name (1R,6S,14S,15S,18S,20S,23R,24S)-20-hydroxy-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacos-2(11)-en-17-one
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 3.8
Gsk 4 400 Rule False
Molecular Formula C27H41NO2
Scaffold Graph Node Bond Level O=C1CC2C3CCC4=C(CN5CCCCC5C4)C3CC2C2CCCCC12
Inchi Key ICSCULPVAJQROK-LMKSZFHCSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 0.0
Synonyms ebeinone
Esol Class Moderately soluble
Functional Groups CC(C)=C(C)C, CC(C)=O, CN(C)C, CO
Compound Name (1R,6S,14S,15S,18S,20S,23R,24S)-20-hydroxy-6,10,23-trimethyl-4-azahexacyclo[12.11.0.02,11.04,9.015,24.018,23]pentacos-2(11)-en-17-one
Exact Mass 411.314
Formal Charge 0.0
Monoisotopic Mass 411.314
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 411.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 10.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C27H41NO2/c1-15-4-7-25-16(2)18-5-6-19-20(22(18)14-28(25)13-15)11-23-21(19)12-26(30)24-10-17(29)8-9-27(23,24)3/h15-17,19-21,23-25,29H,4-14H2,1-3H3/t15-,16?,17-,19+,20+,21-,23-,24+,25?,27+/m0/s1
Smiles C[C@H]1CCC2C(C3=C(CN2C1)[C@@H]4C[C@H]5[C@H]([C@@H]4CC3)CC(=O)[C@@H]6[C@@]5(CC[C@@H](C6)O)C)C
Np Classifier Biosynthetic Pathway Alkaloids, Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Pseudoalkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Fritillaria Imperialis (Plant) Rel Props:Reference:ISBN:9780387706375; ISBN:9788172362300; ISBN:9788185042145