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(3R)-3-[2-(dimethylamino)phenyl]-3-hydroxy-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one

PubChem CID: 101995827

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 56.1
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1C2CCCCC2CC2C(C3CCCCC3)CCC12
Np Classifier Class Quinazoline alkaloids
Deep Smiles CNcccccc6[C@]O)CCnc5ncccccc6c%10=O))))))))))))))))))))C
Heavy Atom Count 24.0
Classyfire Class Diazanaphthalenes
Scaffold Graph Node Level OC1C2CCCCC2NC2C(C3CCCCC3)CCN12
Classyfire Subclass Benzodiazines
Isotope Atom Count 0.0
Molecular Complexity 547.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name (3R)-3-[2-(dimethylamino)phenyl]-3-hydroxy-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 2.0
Gsk 4 400 Rule True
Molecular Formula C19H19N3O2
Scaffold Graph Node Bond Level O=c1c2ccccc2nc2n1CCC2c1ccccc1
Inchi Key MVNPGYCURAKAPD-LJQANCHMSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 2.0
Synonyms desmethoxyaniflorine
Esol Class Soluble
Functional Groups CO, c=O, cN(C)C, cn(c)C, cnc
Compound Name (3R)-3-[2-(dimethylamino)phenyl]-3-hydroxy-1,2-dihydropyrrolo[2,1-b]quinazolin-9-one
Exact Mass 321.148
Formal Charge 0.0
Monoisotopic Mass 321.148
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 321.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C19H19N3O2/c1-21(2)16-10-6-4-8-14(16)19(24)11-12-22-17(23)13-7-3-5-9-15(13)20-18(19)22/h3-10,24H,11-12H2,1-2H3/t19-/m1/s1
Smiles CN(C)C1=CC=CC=C1[C@@]2(CCN3C2=NC4=CC=CC=C4C3=O)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Anthranilic acid alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Justicia Adhatoda (Plant) Rel Props:Reference:ISBN:9770972795006