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(13aR)-3-methoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-2-ol

PubChem CID: 101946254

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 32.7
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2CC3C(CCC4CCCCC43)CC2C1
Np Classifier Class Isoquinoline alkaloids, Protoberberine alkaloids
Deep Smiles COcccCCN[C@@H]c6cc%10O))))CccC6)cccc6
Heavy Atom Count 21.0
Classyfire Class Protoberberine alkaloids and derivatives
Scaffold Graph Node Level C1CCC2CN3CCC4CCCCC4C3CC2C1
Isotope Atom Count 0.0
Molecular Complexity 374.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name (13aR)-3-methoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-2-ol
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 3.0
Gsk 4 400 Rule True
Molecular Formula C18H19NO2
Scaffold Graph Node Bond Level c1ccc2c(c1)CC1c3ccccc3CCN1C2
Inchi Key FNYIPYRLIHJQLI-MRXNPFEDSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 1.0
Synonyms bharatamine
Esol Class Soluble
Functional Groups CN(C)C, cO, cOC
Compound Name (13aR)-3-methoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-2-ol
Exact Mass 281.142
Formal Charge 0.0
Monoisotopic Mass 281.142
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 281.3
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C18H19NO2/c1-21-18-9-13-6-7-19-11-14-5-3-2-4-12(14)8-16(19)15(13)10-17(18)20/h2-5,9-10,16,20H,6-8,11H2,1H3/t16-/m1/s1
Smiles COC1=C(C=C2[C@H]3CC4=CC=CC=C4CN3CCC2=C1)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Alangium Salviifolium (Plant) Rel Props:Reference:ISBN:9788172361150; ISBN:9788185042138; ISBN:9788185042145