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methyl (1S,6Z,7S,9S,10S,12S,20R)-6-ethylidene-10-hydroxy-13-methyl-11-oxa-4,13-diazahexacyclo[10.7.1.01,10.04,9.07,20.014,19]icosa-14,16,18-triene-20-carboxylate

PubChem CID: 101712482

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 62.2
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CCC34C5CCCCC5CC5CC3C2CC1C54
Np Classifier Class Corynanthe type
Deep Smiles COC=O)[C@][C@H]C[C@H][C@@][C@@]6CCN6C/C/%10=CC)))))))ccN[C@H]%10O7))C))cccc6)))))))O
Heavy Atom Count 28.0
Classyfire Class Quinolines and derivatives
Scaffold Graph Node Level CC1CN2CCC34C5CCCCC5NC5OC3C2CC1C54
Classyfire Subclass Benzoquinolines
Isotope Atom Count 0.0
Molecular Complexity 770.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name methyl (1S,6Z,7S,9S,10S,12S,20R)-6-ethylidene-10-hydroxy-13-methyl-11-oxa-4,13-diazahexacyclo[10.7.1.01,10.04,9.07,20.014,19]icosa-14,16,18-triene-20-carboxylate
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 1.3
Gsk 4 400 Rule True
Molecular Formula C22H26N2O4
Scaffold Graph Node Bond Level C=C1CN2CCC34c5ccccc5NC5OC3C2CC1C54
Inchi Key YWHJXIKKMXPHRE-OWRVXNJMSA-N
Silicos It Class Soluble
Rotatable Bond Count 2.0
Synonyms lanceomigine
Esol Class Soluble
Functional Groups C/C=C(C)C, CN(C)C, COC(C)=O, cN(C)[C@@H]1CC[C@](C)(O)O1
Compound Name methyl (1S,6Z,7S,9S,10S,12S,20R)-6-ethylidene-10-hydroxy-13-methyl-11-oxa-4,13-diazahexacyclo[10.7.1.01,10.04,9.07,20.014,19]icosa-14,16,18-triene-20-carboxylate
Exact Mass 382.189
Formal Charge 0.0
Monoisotopic Mass 382.189
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 382.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C22H26N2O4/c1-4-13-12-24-10-9-20-14-7-5-6-8-16(14)23(2)18-21(20,19(25)27-3)15(13)11-17(24)22(20,26)28-18/h4-8,15,17-18,26H,9-12H2,1-3H3/b13-4+/t15-,17-,18-,20-,21+,22+/m0/s1
Smiles C/C=C/1\CN2CC[C@]34C5=CC=CC=C5N([C@@H]6[C@]3([C@H]1C[C@H]2[C@]4(O6)O)C(=O)OC)C
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Hunteria Zeylanica (Plant) Rel Props:Reference:ISBN:9788185042114
  • 2. Outgoing r'ship FOUND_IN to/from Vinca Major (Plant) Rel Props:Reference:ISBN:9788172363093