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[(1S,3Z,5S,7S,10S,13R)-13-acetyloxy-2,7,10-trihydroxy-8,12,15,15-tetramethyl-9-oxo-5-tricyclo[9.3.1.14,8]hexadeca-3,11-dienyl] (2S,3R)-3-(dimethylamino)-2-hydroxy-3-phenylpropanoate

PubChem CID: 101676778

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Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 154.0
Hydrogen Bond Donor Count 4.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC(CCC1CCCCC1)CC1CCC2CC1CCC1CCCC(C1)CC2C
Np Classifier Class Taxane diterpenoids
Deep Smiles CC=O)O[C@@H]C[C@@H]CO)/C=CCCC=O)[C@H]C=C%12C))C%10C)C)))O)))C)[C@H]C[C@@H]6OC=O)[C@H][C@@H]cccccc6))))))NC)C)))O))))))O
Heavy Atom Count 43.0
Classyfire Class Fatty acyls
Scaffold Graph Node Level OC(CCC1CCCCC1)OC1CCC2CC1CCC1CCCC(C1)CC2O
Classyfire Subclass Fatty acid esters
Isotope Atom Count 0.0
Molecular Complexity 1150.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 7.0
Iupac Name [(1S,3Z,5S,7S,10S,13R)-13-acetyloxy-2,7,10-trihydroxy-8,12,15,15-tetramethyl-9-oxo-5-tricyclo[9.3.1.14,8]hexadeca-3,11-dienyl] (2S,3R)-3-(dimethylamino)-2-hydroxy-3-phenylpropanoate
Prediction Hob 0.0
Veber Rule False
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 1.1
Gsk 4 400 Rule False
Molecular Formula C33H45NO9
Scaffold Graph Node Bond Level O=C(CCc1ccccc1)OC1CCC2CC1=CCC1CCC=C(CC2=O)C1
Prediction Swissadme 0.0
Inchi Key ONNIMFBTDSHYJD-VXYCCGDRSA-N
Silicos It Class Soluble
Fcsp3 0.6060606060606061
Logs -3.785
Rotatable Bond Count 8.0
Logd 2.101
Synonyms 2-deacetyl taxine a
Esol Class Soluble
Functional Groups C/C=C(C)C, CC(=O)OC, CC(C)=C(C)C, CC(C)=O, CN(C)C, CO, COC(C)=O
Compound Name [(1S,3Z,5S,7S,10S,13R)-13-acetyloxy-2,7,10-trihydroxy-8,12,15,15-tetramethyl-9-oxo-5-tricyclo[9.3.1.14,8]hexadeca-3,11-dienyl] (2S,3R)-3-(dimethylamino)-2-hydroxy-3-phenylpropanoate
Prediction Hob Swissadme 0.0
Exact Mass 599.309
Formal Charge 0.0
Monoisotopic Mass 599.309
Hydrogen Bond Acceptor Count 10.0
Molecular Weight 599.7
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Esol -3.80132601395349
Inchi InChI=1S/C33H45NO9/c1-17-23(42-18(2)35)14-21-22(36)13-20-16-33(5,30(40)28(38)26(17)32(21,3)4)25(37)15-24(20)43-31(41)29(39)27(34(6)7)19-11-9-8-10-12-19/h8-13,21-25,27-29,36-39H,14-16H2,1-7H3/b20-13-/t21-,22?,23-,24+,25+,27-,28+,29+,33?/m1/s1
Smiles CC1=C2[C@@H](C(=O)C3(C/C(=C/C([C@H](C2(C)C)C[C@H]1OC(=O)C)O)/[C@H](C[C@@H]3O)OC(=O)[C@H]([C@@H](C4=CC=CC=C4)N(C)C)O)C)O
Nring 4.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 1.0
Egan Rule False
Np Classifier Superclass Diterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Taxus Baccata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all