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(1R,2R,3S,6R,7S,8S,10S)-2-ethyl-8-hydroxy-6-methyl-10-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]-4-oxa-11-azatetracyclo[9.4.1.01,8.03,7]hexadecane-5,16-dione

PubChem CID: 101670618

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 93.1
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCC(C2CC3C4CC(C)CC4CC34CCCCC2C4C)C1
Np Classifier Class Stemona alkaloids
Deep Smiles CC[C@H][C@@H]OC=O)[C@@H][C@@H]5[C@@][C@@]8CCCCNC7=O))[C@@H]C9)[C@@H]C[C@@H]C=O)O5))C)))))))))))O)))C
Heavy Atom Count 29.0
Classyfire Class Lactams
Scaffold Graph Node Level OC1CC2C(CC34CCCCN(C(C5CCC(O)O5)CC23)C4O)O1
Classyfire Subclass Caprolactams
Isotope Atom Count 0.0
Molecular Complexity 768.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 9.0
Iupac Name (1R,2R,3S,6R,7S,8S,10S)-2-ethyl-8-hydroxy-6-methyl-10-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]-4-oxa-11-azatetracyclo[9.4.1.01,8.03,7]hexadecane-5,16-dione
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 1.8
Gsk 4 400 Rule False
Molecular Formula C22H31NO6
Scaffold Graph Node Bond Level O=C1CC2C(CC34CCCCN(C3=O)C(C3CCC(=O)O3)CC24)O1
Inchi Key YOBIPOVYJKVGIS-QHSDLTJRSA-N
Silicos It Class Soluble
Rotatable Bond Count 2.0
Synonyms tuberostemoninol
Esol Class Soluble
Functional Groups CN(C)C(C)=O, CO, COC(C)=O
Compound Name (1R,2R,3S,6R,7S,8S,10S)-2-ethyl-8-hydroxy-6-methyl-10-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]-4-oxa-11-azatetracyclo[9.4.1.01,8.03,7]hexadecane-5,16-dione
Exact Mass 405.215
Formal Charge 0.0
Monoisotopic Mass 405.215
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 405.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C22H31NO6/c1-4-13-17-16(12(3)19(25)29-17)22(27)10-14(15-9-11(2)18(24)28-15)23-8-6-5-7-21(13,22)20(23)26/h11-17,27H,4-10H2,1-3H3/t11-,12+,13-,14-,15-,16-,17-,21-,22-/m0/s1
Smiles CC[C@H]1[C@H]2[C@H]([C@H](C(=O)O2)C)[C@@]3([C@@]14CCCCN(C4=O)[C@@H](C3)[C@@H]5C[C@@H](C(=O)O5)C)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Ornithine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Stemona Tuberosa (Plant) Rel Props:Reference:ISBN:9788172363093; ISBN:9788185042145