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1-[(12S,13R,14R,19R,21S)-14-hydroxy-15-oxa-1,11-diazahexacyclo[16.3.1.04,12.04,21.05,10.013,19]docosa-5,7,9,17-tetraen-11-yl]ethanone

PubChem CID: 101667973

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 53.0
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C3CC4C(CCC45C4CCCCC4CC25)CC3C1
Np Classifier Class Corynanthe type, Strychnos type
Deep Smiles O[C@@H]OCC=C[C@H][C@@H]7[C@@H]NC=O)C))ccC5[C@H]C9)NC%11)CC5)))))cccc6
Heavy Atom Count 26.0
Classyfire Class Strychnos alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1C3COCCC4CN5CCC21C5CC43
Isotope Atom Count 0.0
Molecular Complexity 678.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 5.0
Iupac Name 1-[(12S,13R,14R,19R,21S)-14-hydroxy-15-oxa-1,11-diazahexacyclo[16.3.1.04,12.04,21.05,10.013,19]docosa-5,7,9,17-tetraen-11-yl]ethanone
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 0.7
Gsk 4 400 Rule True
Molecular Formula C21H24N2O3
Scaffold Graph Node Bond Level C1=C2CN3CCC45c6ccccc6NC4C(COC1)C2CC35
Inchi Key QSDMAJZSSDNJPO-BEADDXDSSA-N
Silicos It Class Soluble
Rotatable Bond Count 0.0
Synonyms diaboline
Esol Class Soluble
Functional Groups CC=C(C)C, CN(C)C, CO[C@H](C)O, cN(C)C(C)=O
Compound Name 1-[(12S,13R,14R,19R,21S)-14-hydroxy-15-oxa-1,11-diazahexacyclo[16.3.1.04,12.04,21.05,10.013,19]docosa-5,7,9,17-tetraen-11-yl]ethanone
Exact Mass 352.179
Formal Charge 0.0
Monoisotopic Mass 352.179
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 352.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H24N2O3/c1-12(24)23-16-5-3-2-4-15(16)21-7-8-22-11-13-6-9-26-20(25)18(19(21)23)14(13)10-17(21)22/h2-6,14,17-20,25H,7-11H2,1H3/t14-,17-,18+,19-,20+,21?/m0/s1
Smiles CC(=O)N1[C@H]2[C@H]3[C@H]4C[C@H]5C2(CCN5CC4=CCO[C@H]3O)C6=CC=CC=C61
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Acacia Polyacantha (Plant) Rel Props:Reference:ISBN:9788190115162
  • 2. Outgoing r'ship FOUND_IN to/from Strychnos Ignatii (Plant) Rel Props:Reference:ISBN:9780387706375
  • 3. Outgoing r'ship FOUND_IN to/from Strychnos Potatorum (Plant) Rel Props:Reference:ISBN:9788172361150; ISBN:9788185042084