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(11S,12R,13S,14R,17S,18S)-17-ethyl-3-methyl-15-oxa-3,20-diazapentacyclo[10.7.1.02,10.04,9.013,18]icosa-2(10),4,6,8-tetraene-11,14-diol

PubChem CID: 101641322

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 66.7
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1CC2CC2C3CCCCC3CC12
Np Classifier Class Carboline alkaloids
Deep Smiles CC[C@@H]CO[C@H][C@H][C@H]6CCN[C@H]6[C@H]cc6nC)cc5cccc6)))))))))O))))))))O
Heavy Atom Count 25.0
Classyfire Class Macroline alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1C3CC4CCOCC4C(CC21)N3
Isotope Atom Count 0.0
Molecular Complexity 517.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name (11S,12R,13S,14R,17S,18S)-17-ethyl-3-methyl-15-oxa-3,20-diazapentacyclo[10.7.1.02,10.04,9.013,18]icosa-2(10),4,6,8-tetraene-11,14-diol
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.3
Gsk 4 400 Rule True
Molecular Formula C20H26N2O3
Scaffold Graph Node Bond Level c1ccc2c3c([nH]c2c1)C1CC2CCOCC2C(C3)N1
Inchi Key MRVRYGOAJGOYRP-OFAOMQSZSA-N
Silicos It Class Soluble
Rotatable Bond Count 1.0
Synonyms 6alpha-hydroxyraumacline
Esol Class Soluble
Functional Groups CNC, CO, CO[C@H](C)O, cn(c)C
Compound Name (11S,12R,13S,14R,17S,18S)-17-ethyl-3-methyl-15-oxa-3,20-diazapentacyclo[10.7.1.02,10.04,9.013,18]icosa-2(10),4,6,8-tetraene-11,14-diol
Exact Mass 342.194
Formal Charge 0.0
Monoisotopic Mass 342.194
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 342.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 7.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C20H26N2O3/c1-3-10-9-25-20(24)15-12(10)8-13-18-16(19(23)17(15)21-13)11-6-4-5-7-14(11)22(18)2/h4-7,10,12-13,15,17,19-21,23-24H,3,8-9H2,1-2H3/t10-,12+,13?,15+,17-,19+,20-/m1/s1
Smiles CC[C@@H]1CO[C@H]([C@H]2[C@H]1CC3C4=C([C@@H]([C@@H]2N3)O)C5=CC=CC=C5N4C)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Rauvolfia Serpentina (Plant) Rel Props:Reference:ISBN:9788185042145