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[(1R)-1-[(1R,2R,5S,6S,7S,8S,11S)-1'-methoxy-4-methyl-2'-oxospiro[9-oxa-4-azatetracyclo[6.3.1.02,6.05,11]dodecane-7,3'-indole]-2-yl]ethyl] acetate

PubChem CID: 101601181

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 68.3
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CCCCC2C12C1CCC3C(C1)C1CCC3C12
Deep Smiles CONcccccc6[C@]C9=O))[C@H]OC[C@@H][C@@H][C@H]7[C@][C@@H]5C9))CN5C)))[C@H]OC=O)C)))C
Heavy Atom Count 30.0
Classyfire Class Gelsemium alkaloids
Scaffold Graph Node Level OC1NC2CCCCC2C12C1CC3C(CO1)C1NCC3C12
Isotope Atom Count 0.0
Molecular Complexity 790.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 8.0
Iupac Name [(1R)-1-[(1R,2R,5S,6S,7S,8S,11S)-1'-methoxy-4-methyl-2'-oxospiro[9-oxa-4-azatetracyclo[6.3.1.02,6.05,11]dodecane-7,3'-indole]-2-yl]ethyl] acetate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.5
Gsk 4 400 Rule False
Molecular Formula C23H28N2O5
Scaffold Graph Node Bond Level O=C1Nc2ccccc2C12C1CC3C(CO1)C1NCC3C12
Inchi Key BTZWFBFZHHQPCI-ANBNLFSGSA-N
Silicos It Class Soluble
Rotatable Bond Count 4.0
Synonyms 19-(r)-acetyldihydrogelsevirine
Esol Class Very soluble
Functional Groups CC(=O)OC, CN(C)C, COC, cN(OC)C(C)=O
Compound Name [(1R)-1-[(1R,2R,5S,6S,7S,8S,11S)-1'-methoxy-4-methyl-2'-oxospiro[9-oxa-4-azatetracyclo[6.3.1.02,6.05,11]dodecane-7,3'-indole]-2-yl]ethyl] acetate
Exact Mass 412.2
Formal Charge 0.0
Monoisotopic Mass 412.2
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 412.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C23H28N2O5/c1-12(30-13(2)26)22-11-24(3)19-14-10-29-18(9-16(14)22)23(20(19)22)15-7-5-6-8-17(15)25(28-4)21(23)27/h5-8,12,14,16,18-20H,9-11H2,1-4H3/t12-,14+,16-,18+,19-,20+,22-,23+/m1/s1
Smiles C[C@H]([C@@]12CN([C@H]3[C@@H]1[C@@]4([C@@H]5C[C@@H]2[C@@H]3CO5)C6=CC=CC=C6N(C4=O)OC)C)OC(=O)C
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True

  • 1. Outgoing r'ship FOUND_IN to/from Gelsemium Elegans (Plant) Rel Props:Reference:ISBN:9788172362300