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Nuciferine

PubChem CID: 10146

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Compound Synonyms Nuciferine, 475-83-2, Nuciferin, l-Nuciferine, Sanjoinine E, (-)-Nucipherine, (-)-nuciferine, (R)-1,2-Dimethoxyaporphine, 1,2-Dimethoxy-6abeta-aporphine, UNII-W26UEB90B7, W26UEB90B7, (6ar)-1,2-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4h-dibenzo[de,g]quinoline, (R)-1,2-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline, (R)-NUCIFERINE, D-(-)-NUCIFERINE, 1-5, 6-Dimethoxyaporphine, 4H-Dibenzo(de,g)quinoline, 5,6,6a,7-tetrahydro-1,2-dimethoxy-6-methyl-, (R)-, 6a-beta-APORPHINE, 1,2-DIMETHOXY-, 6a-.beta.-Aporphine, 1,2-dimethoxy-, 1,2-DIMETHOXY-6A.BETA.-APORPHINE, l-5,6-Dimethoxyaporphine, 4H-DIBENZO(DE,G)QUINOLINE, 5,6,6A,7-TETRAHYDRO-1,2-DIMETHOXY-6-METHYL-, (6AR)-, DTXSID40963862, (6aR)-1,2-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo(de,g)quinoline, Nuciferine (Standard), CHEMBL464529, Nuciferine - Bio-X trade mark, SCHEMBL20544868, HY-N0049R, HMS3887A19, HY-N0049, MFCD01664592, NSC785145, s3821, AKOS015903258, AC-7998, CCG-267422, CS-4270, FN65106, NSC-785145, 1ST40326, BN300106, BS-42200, N1170, NS00067009, AG-690/36921306, Q7067904, 4H-Dibenzo(de,g)quinoline, 5,6,6a,7-tetrahydro-1,2-dimethoxy-6-methyl-, (R)-(9CI), 842-235-9
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 21.7
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1CCCC3CCCC2C31
Np Classifier Class Aporphine alkaloids, Isoquinoline alkaloids
Deep Smiles COcccCCN[C@H]c6c-cccccc6C%10)))))))c%10OC))))))C
Heavy Atom Count 22.0
Classyfire Class Aporphines
Scaffold Graph Node Level C1CCC2C(C1)CC1NCCC3CCCC2C31
Isotope Atom Count 0.0
Molecular Complexity 401.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 1.0
Uniprot Id O42713, n.a., P28335, P41595, P28223, P35348, P35368, P25100
Iupac Name (6aR)-1,2-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 3.4
Gsk 4 400 Rule True
Molecular Formula C19H21NO2
Scaffold Graph Node Bond Level c1ccc2c(c1)CC1NCCc3cccc-2c31
Prediction Swissadme 1.0
Inchi Key ORJVQPIHKOARKV-OAHLLOKOSA-N
Silicos It Class Moderately soluble
Fcsp3 0.3684210526315789
Logs -3.201
Rotatable Bond Count 2.0
Logd 2.934
Synonyms nuciferin, nuciferine
Esol Class Moderately soluble
Functional Groups CN(C)C, cOC
Compound Name Nuciferine
Prediction Hob Swissadme 1.0
Exact Mass 295.157
Formal Charge 0.0
Monoisotopic Mass 295.157
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 295.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.103904763636364
Inchi InChI=1S/C19H21NO2/c1-20-9-8-13-11-16(21-2)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,11,15H,8-10H2,1-3H3/t15-/m1/s1
Smiles CN1CCC2=CC(=C(C3=C2[C@H]1CC4=CC=CC=C43)OC)OC
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

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