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4-hydroxy-3-[4-[[(5S)-11-methoxy-6,19-dimethyl-20-oxo-2,13-dioxa-6,19-diazapentacyclo[12.8.0.03,12.04,9.016,21]docosa-1(14),3,9,11,15,21-hexaen-5-yl]methyl]phenoxy]benzaldehyde

PubChem CID: 101428301

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Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 97.8
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCCC2CC3CC4CCC5CCCC(CC6CCC(CC7CCCCC7)CC6)C5C4CC3CC12
Np Classifier Class Isoquinoline alkaloids
Deep Smiles O=Ccccccc6)Occcccc6))C[C@@H]NC)CCcc6cOcccccc6Oc%10cc%14)OC)))))))CCNC6=O))C)))))))))))))))))))))))O
Heavy Atom Count 44.0
Classyfire Class Isoquinolines and derivatives
Scaffold Graph Node Level OC1NCCC2CC3OC4CCC5CCNC(CC6CCC(OC7CCCCC7)CC6)C5C4OC3CC21
Classyfire Subclass Benzylisoquinolines
Isotope Atom Count 0.0
Molecular Complexity 1020.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name 4-hydroxy-3-[4-[[(5S)-11-methoxy-6,19-dimethyl-20-oxo-2,13-dioxa-6,19-diazapentacyclo[12.8.0.03,12.04,9.016,21]docosa-1(14),3,9,11,15,21-hexaen-5-yl]methyl]phenoxy]benzaldehyde
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 5.0
Gsk 4 400 Rule False
Molecular Formula C35H32N2O7
Scaffold Graph Node Bond Level O=C1NCCc2cc3c(cc21)Oc1c(ccc2c1C(Cc1ccc(Oc4ccccc4)cc1)NCC2)O3
Prediction Swissadme 0.0
Inchi Key WUUQNVFSQHFGSF-SANMLTNESA-N
Silicos It Class Poorly soluble
Fcsp3 0.2571428571428571
Logs -4.755
Rotatable Bond Count 6.0
Logd 0.968
Synonyms punjabine
Esol Class Poorly soluble
Functional Groups CN(C)C, cC(=O)N(C)C, cC=O, cO, cOC, cOc
Compound Name 4-hydroxy-3-[4-[[(5S)-11-methoxy-6,19-dimethyl-20-oxo-2,13-dioxa-6,19-diazapentacyclo[12.8.0.03,12.04,9.016,21]docosa-1(14),3,9,11,15,21-hexaen-5-yl]methyl]phenoxy]benzaldehyde
Prediction Hob Swissadme 0.0
Exact Mass 592.221
Formal Charge 0.0
Monoisotopic Mass 592.221
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 592.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 False
Esol -6.684653963636365
Inchi InChI=1S/C35H32N2O7/c1-36-12-11-23-17-31(41-3)33-34(44-30-18-25-22(16-29(30)43-33)10-13-37(2)35(25)40)32(23)26(36)14-20-4-7-24(8-5-20)42-28-15-21(19-38)6-9-27(28)39/h4-9,15-19,26,39H,10-14H2,1-3H3/t26-/m0/s1
Smiles CN1CCC2=CC(=C3C(=C2[C@@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C=O)O)OC6=C(O3)C=C7CCN(C(=O)C7=C6)C)OC
Nring 8.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Np Classifier Superclass Tyrosine alkaloids