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methyl (1S,3R,4aS,5aS,6S,10aR)-3-hydroxy-1-methyl-2'-oxospiro[1,3,4,4a,5,5a,7,8,10,10a-decahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate

PubChem CID: 101418806

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 88.1
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CC2CCCCC2C12CCC1CC3CCCCC3CC12
Np Classifier Class Strychnos type
Deep Smiles COC=O)C[C@H]O)O[C@H][C@@H][C@@H]6C[C@@H]NC6)CC[C@@]5C=O)Ncc5cccc6))))))))))))))))C
Heavy Atom Count 28.0
Classyfire Class Yohimbine alkaloids
Scaffold Graph Node Level OC1NC2CCCCC2C12CCN1CC3COCCC3CC12
Isotope Atom Count 0.0
Molecular Complexity 671.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name methyl (1S,3R,4aS,5aS,6S,10aR)-3-hydroxy-1-methyl-2'-oxospiro[1,3,4,4a,5,5a,7,8,10,10a-decahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.5
Gsk 4 400 Rule True
Molecular Formula C21H26N2O5
Scaffold Graph Node Bond Level O=C1Nc2ccccc2C12CCN1CC3COCCC3CC12
Inchi Key BZEARLNMWSCOOH-NHZNEJAVSA-N
Silicos It Class Soluble
Rotatable Bond Count 2.0
Synonyms 16,17-dihydro-17beta-hydroxyisomitraphylline
Esol Class Soluble
Functional Groups CN(C)C, COC(C)=O, C[C@H](O)OC, cNC(C)=O
Compound Name methyl (1S,3R,4aS,5aS,6S,10aR)-3-hydroxy-1-methyl-2'-oxospiro[1,3,4,4a,5,5a,7,8,10,10a-decahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
Exact Mass 386.184
Formal Charge 0.0
Monoisotopic Mass 386.184
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 386.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 7.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H26N2O5/c1-11-13-10-23-8-7-21(14-5-3-4-6-15(14)22-20(21)26)16(23)9-12(13)17(18(24)27-2)19(25)28-11/h3-6,11-13,16-17,19,25H,7-10H2,1-2H3,(H,22,26)/t11-,12-,13+,16-,17?,19+,21-/m0/s1
Smiles C[C@H]1[C@H]2CN3CC[C@@]4([C@@H]3C[C@@H]2C([C@@H](O1)O)C(=O)OC)C5=CC=CC=C5NC4=O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Mitragyna Parvifolia (Plant) Rel Props:Reference:ISBN:9770972795006