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(1R,2R,6S,9R,11S)-2-hydroxy-9,11,14,14-tetramethyl-6-phenyl-7,12-dioxatetracyclo[7.4.1.02,11.03,8]tetradec-3(8)-ene-4,10-dione

PubChem CID: 101324818

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 72.8
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC(C2CCCCC2)CC2C3CC4CCC(C3C)C4C12
Deep Smiles O=CC[C@H]OC=C6[C@]O)[C@@H]C[C@@]6C)C=O)[C@@]6C)OC7)))))C)C)))))))cccccc6
Heavy Atom Count 27.0
Classyfire Class Oxepanes
Scaffold Graph Node Level OC1CC(C2CCCCC2)OC2C3CC4COC(C3O)C4C12
Isotope Atom Count 0.0
Molecular Complexity 776.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 5.0
Iupac Name (1R,2R,6S,9R,11S)-2-hydroxy-9,11,14,14-tetramethyl-6-phenyl-7,12-dioxatetracyclo[7.4.1.02,11.03,8]tetradec-3(8)-ene-4,10-dione
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 1.5
Gsk 4 400 Rule True
Molecular Formula C22H24O5
Scaffold Graph Node Bond Level O=C1CC(c2ccccc2)OC2=C1C1C3COC1C(=O)C2C3
Prediction Swissadme 1.0
Inchi Key NZANVYUIDHOMEY-VTKNXMALSA-N
Silicos It Class Moderately soluble
Fcsp3 0.5454545454545454
Logs -3.865
Rotatable Bond Count 1.0
Logd 1.521
Synonyms louisfieserone
Esol Class Soluble
Functional Groups CC(C)=O, CC1=C(C)C(=O)CCO1, CO, COC
Compound Name (1R,2R,6S,9R,11S)-2-hydroxy-9,11,14,14-tetramethyl-6-phenyl-7,12-dioxatetracyclo[7.4.1.02,11.03,8]tetradec-3(8)-ene-4,10-dione
Prediction Hob Swissadme 1.0
Exact Mass 368.162
Formal Charge 0.0
Monoisotopic Mass 368.162
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 368.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.1425042444444444
Inchi InChI=1S/C22H24O5/c1-19(2)15-11-26-21(4)18(24)20(19,3)17-16(22(15,21)25)13(23)10-14(27-17)12-8-6-5-7-9-12/h5-9,14-15,25H,10-11H2,1-4H3/t14-,15-,20+,21+,22+/m0/s1
Smiles C[C@]12C3=C(C(=O)C[C@H](O3)C4=CC=CC=C4)[C@@]5([C@H](C1(C)C)CO[C@@]5(C2=O)C)O
Nring 3.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids, Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True

  • 1. Outgoing r'ship FOUND_IN to/from Astragalus Complanatus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Brassica Juncea (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Calophyllum Teysmannii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Indigofera Oblongifolia (Plant) Rel Props:Reference:ISBN:9770972795006
  • 5. Outgoing r'ship FOUND_IN to/from Indigofera Suffruticosa (Plant) Rel Props:Reference:ISBN:9788185042084