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[(1S,8'R)-7-hydroxy-6-methoxy-2-methylspiro[3,4-dihydroisoquinoline-1,7'-6,8-dihydrocyclopenta[g][1,3]benzodioxole]-8'-yl] acetate

PubChem CID: 101316764

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 77.5
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule True
Scaffold Graph Level C1CCC2C(C1)CCCC21CC2CCC3CCCC3C2C1
Np Classifier Class Isoquinoline alkaloids
Deep Smiles COcccCCN[C@]c6cc%10O))))Ccc[C@H]5OC=O)C))))cOCOc5cc9)))))))))))C
Heavy Atom Count 29.0
Classyfire Class Tetrahydroisoquinolines
Scaffold Graph Node Level C1CCC2C(C1)CCNC21CC2CCC3OCOC3C2C1
Isotope Atom Count 0.0
Molecular Complexity 645.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name [(1S,8'R)-7-hydroxy-6-methoxy-2-methylspiro[3,4-dihydroisoquinoline-1,7'-6,8-dihydrocyclopenta[g][1,3]benzodioxole]-8'-yl] acetate
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 2.5
Gsk 4 400 Rule True
Molecular Formula C22H23NO6
Scaffold Graph Node Bond Level c1ccc2c(c1)CCNC21Cc2ccc3c(c2C1)OCO3
Inchi Key VIRGMCFNCOBYML-YADHBBJMSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 3.0
Synonyms fumarophycine
Esol Class Moderately soluble
Functional Groups CC(=O)OC, CN(C)C, c1cOCO1, cO, cOC
Compound Name [(1S,8'R)-7-hydroxy-6-methoxy-2-methylspiro[3,4-dihydroisoquinoline-1,7'-6,8-dihydrocyclopenta[g][1,3]benzodioxole]-8'-yl] acetate
Exact Mass 397.153
Formal Charge 0.0
Monoisotopic Mass 397.153
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 397.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C22H23NO6/c1-12(24)29-21-19-14(4-5-17-20(19)28-11-27-17)10-22(21)15-9-16(25)18(26-3)8-13(15)6-7-23(22)2/h4-5,8-9,21,25H,6-7,10-11H2,1-3H3/t21-,22+/m1/s1
Smiles CC(=O)O[C@@H]1C2=C(C[C@]13C4=CC(=C(C=C4CCN3C)OC)O)C=CC5=C2OCO5
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Fumaria Officinalis (Plant) Rel Props:Reference:https://doi.org/10.2174/0929867033456729