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Corydaline

PubChem CID: 101301

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Compound Synonyms Corydaline, 518-69-4, (+)-Corydaline, (+/-)-Corydaline, d-Corydaline, Corydaline, (+/-)-, Corydaline DL-form [MI], NSC-298182, 6MUC9717YK, (13S,13aR)-2,3,9,10-tetramethoxy-13-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline, CHEBI:14027, 08N392L8VX, NSC 406036, (13SR,13Ars)-5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-6H-dibenzo(a,g)-quinolizine, 6H-Dibenzo(a,g)quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-, (13R,13aS)-rel-, 6H-Dibenzo(a,g)quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-, trans-(+/-)-, 2,3,9,10-tetramethoxy-13beta-methyl-13abeta-berbine, Berbine, 2,3,9,10-tetramethoxy-13-methyl-, 6018-35-5, (13S,13aR)-2,3,9,10-tetramethoxy-13-methyl-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline, (+)-Corydaline, Corydalin, BRN 0096972, UNII-6MUC9717YK, UNII-08N392L8VX, NSC-406036, (+)Corydaline, 6H-Dibenzo(a,g)quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-, (13S-trans)-, (+)- Corydaline, Corydaline (Standard), CORYDALINE [MI], 5-21-06-00173 (Beilstein Handbook Reference), 6H-Dibenzo(a,g)quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-, (13S-E)-, SCHEMBL230676, MEGxp0_000624, CHEMBL2165401, ACon0_001192, ACon1_000349, HY-N0923R, 13abeta-Berbine, 2,3,9,10-tetramethoxy-13alpha-methyl-, DTXSID90199735, TCMDC-143075, 13a-beta-Berbine, 2,3,9,10-tetramethoxy-13-alpha-methyl-, Berbine, 2,3,9,10-tetramethoxy-13beta-methyl-, (+/-)-, EX-A6789, HY-N0923, MSK170239, s9252, AKOS030242363, CCG-208480, CS-4248, FC52358, AC-35003, DA-62466, NS00094840, 7,8,13,13.ALPHA.-TETRAHYDROCORYDALINE, SR-05000002225, SR-05000002225-2, BRD-K13148078-001-01-2, Q15410920, (+)-CorydalineCorydalin, (+/-)-Corydaline, d-Corydaline, BERBINE, 2,3,9,10-TETRAMETHOXY-13.BETA.-METHYL-, (+/-)-, (13S,13AR)-5,8,13,13A-TETRAHYDRO-2,3,9,10-TETRAMETHOXY-13-METHYL-6H-DIBENZO(A,G)-QUINOLIZINE, 6H-DIBENZO(A,G)QUINOLIZINE, 5,8,13,13A-TETRAHYDRO-2,3,9,10-TETRAMETHOXY-13-METHYL-, (13S,13AR)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 40.2
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2CC3C(CCC4CCCCC43)CC2C1
Np Classifier Class Isoquinoline alkaloids, Protoberberine alkaloids
Deep Smiles COcccCCN[C@@H]c6cc%10OC)))))[C@@H]C)ccC6)cOC))ccc6))OC
Heavy Atom Count 27.0
Classyfire Class Protoberberine alkaloids and derivatives
Scaffold Graph Node Level C1CCC2CN3CCC4CCCCC4C3CC2C1
Isotope Atom Count 0.0
Molecular Complexity 503.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 2.0
Uniprot Id O42275, P81908, Q7Z1V1
Iupac Name (13S,13aR)-2,3,9,10-tetramethoxy-13-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 3.6
Gsk 4 400 Rule True
Molecular Formula C22H27NO4
Scaffold Graph Node Bond Level c1ccc2c(c1)CC1c3ccccc3CCN1C2
Prediction Swissadme 1.0
Inchi Key VRSRXLJTYQVOHC-YEJXKQKISA-N
Silicos It Class Poorly soluble
Fcsp3 0.4545454545454545
Logs -2.905
Rotatable Bond Count 4.0
Logd 3.305
Synonyms corydaline
Esol Class Moderately soluble
Functional Groups CN(C)C, cOC
Compound Name Corydaline
Prediction Hob Swissadme 1.0
Exact Mass 369.194
Formal Charge 0.0
Monoisotopic Mass 369.194
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 369.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.444647088888889
Inchi InChI=1S/C22H27NO4/c1-13-15-6-7-18(24-2)22(27-5)17(15)12-23-9-8-14-10-19(25-3)20(26-4)11-16(14)21(13)23/h6-7,10-11,13,21H,8-9,12H2,1-5H3/t13-,21+/m0/s1
Smiles C[C@@H]1[C@@H]2C3=CC(=C(C=C3CCN2CC4=C1C=CC(=C4OC)OC)OC)OC
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Corydalis Ternata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Corydalis Tuberosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Corydalis Turtschaninovii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Corydalis Yanhusuo (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Dovyalis Hebecarpa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Eremophila Oppositifolia (Plant) Rel Props:Source_db:npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Fibraurea Recisa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Fumaria Officinalis (Plant) Rel Props:Reference:ISBN:9788185042053; ISBN:9788185042145
  • 9. Outgoing r'ship FOUND_IN to/from Ixeris Repens (Plant) Rel Props:Source_db:npass_chem_all
  • 10. Outgoing r'ship FOUND_IN to/from Lycopodium Chinense (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Taxillus Yadoriki (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all