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(1R,4R,5R)-2,4'-dimethylspiro[2-azabicyclo[2.2.2]octane-5,2'-3H-pyran]-6'-one

PubChem CID: 101289683

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 29.5
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCCC2(C1)CC1CCC2CC1
Np Classifier Class Piperidine alkaloids
Deep Smiles CC=CC=O)O[C@]C6)C[C@H]CC[C@@H]6CN6C
Heavy Atom Count 16.0
Classyfire Class Azaspirodecane derivatives
Scaffold Graph Node Level OC1CCCC2(CC3CCC2CN3)O1
Isotope Atom Count 0.0
Molecular Complexity 363.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 3.0
Iupac Name (1R,4R,5R)-2,4'-dimethylspiro[2-azabicyclo[2.2.2]octane-5,2'-3H-pyran]-6'-one
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 1.5
Gsk 4 400 Rule True
Molecular Formula C13H19NO2
Scaffold Graph Node Bond Level O=C1C=CCC2(CC3CCC2CN3)O1
Inchi Key YBQKKTNDAXVYGX-NQBHXWOUSA-N
Silicos It Class Soluble
Rotatable Bond Count 0.0
Synonyms dioscorine
Esol Class Soluble
Functional Groups CC1=CC(=O)OCC1, CN(C)C
Compound Name (1R,4R,5R)-2,4'-dimethylspiro[2-azabicyclo[2.2.2]octane-5,2'-3H-pyran]-6'-one
Exact Mass 221.142
Formal Charge 0.0
Monoisotopic Mass 221.142
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 221.29
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C13H19NO2/c1-9-5-12(15)16-13(6-9)7-11-4-3-10(13)8-14(11)2/h5,10-11H,3-4,6-8H2,1-2H3/t10-,11-,13-/m1/s1
Smiles CC1=CC(=O)O[C@]2(C1)C[C@H]3CC[C@@H]2CN3C
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Lysine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Dioscorea Hispida (Plant) Rel Props:Reference:ISBN:9780387706375; ISBN:9788172360481; ISBN:9788172361266
  • 2. Outgoing r'ship FOUND_IN to/from Dioscorea Pentaphylla (Plant) Rel Props:Reference:ISBN:9788172360481