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[(1R,9R,10R,12R,19S,20R)-20-methyl-8,16-diazahexacyclo[10.6.1.19,12.01,9.02,7.016,19]icosa-2,4,6,13-tetraen-10-yl]methanol

PubChem CID: 101287751

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 35.5
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC13CCC4(CCCC5CCC21C54)C3
Np Classifier Class Aspidosperma type
Deep Smiles OC[C@@H]C[C@@][C@H][C@@]5Ncc[C@]5[C@H]8NCC5))CC=C%12))))))cccc6))))))))C
Heavy Atom Count 23.0
Classyfire Class Indoles and derivatives
Scaffold Graph Node Level C1CCC2C(C1)NC13CCC4(CCCN5CCC21C54)C3
Classyfire Subclass Carbazoles
Isotope Atom Count 0.0
Molecular Complexity 590.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name [(1R,9R,10R,12R,19S,20R)-20-methyl-8,16-diazahexacyclo[10.6.1.19,12.01,9.02,7.016,19]icosa-2,4,6,13-tetraen-10-yl]methanol
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 2.6
Gsk 4 400 Rule True
Molecular Formula C20H24N2O
Scaffold Graph Node Bond Level C1=CC23CCC4(C2)Nc2ccccc2C42CCN(C1)C32
Inchi Key GDTCUJQHGGXGJM-RHOFUAETSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 1.0
Synonyms vindolininol
Esol Class Soluble
Functional Groups CC=CC, CN(C)C, CO, cNC
Compound Name [(1R,9R,10R,12R,19S,20R)-20-methyl-8,16-diazahexacyclo[10.6.1.19,12.01,9.02,7.016,19]icosa-2,4,6,13-tetraen-10-yl]methanol
Exact Mass 308.189
Formal Charge 0.0
Monoisotopic Mass 308.189
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 308.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C20H24N2O/c1-13-18-7-4-9-22-10-8-19(17(18)22)15-5-2-3-6-16(15)21-20(13,19)14(11-18)12-23/h2-7,13-14,17,21,23H,8-12H2,1H3/t13-,14+,17+,18+,19-,20-/m1/s1
Smiles C[C@@H]1[C@]23C[C@H]([C@@]14[C@@]5([C@H]2N(CC5)CC=C3)C6=CC=CC=C6N4)CO
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Catharanthus Roseus (Plant) Rel Props:Reference:https://doi.org/10.1093/database/bav075