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methyl (1S,10S,15R,17S,18S)-17-ethyl-10-hydroxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2,4,6,8-tetraene-1-carboxylate

PubChem CID: 101286287

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 62.1
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1C2CCC2CC3CCC2C1C3
Np Classifier Class Iboga type
Deep Smiles CC[C@H]C[C@H]CN[C@@H]6[C@]C6)C=O)OC)))C=Ncc[C@]5CC%10))O))cccc6
Heavy Atom Count 26.0
Classyfire Class Ibogan-type alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1C2CCN2CC3CCC2C1C3
Isotope Atom Count 0.0
Molecular Complexity 649.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 5.0
Iupac Name methyl (1S,10S,15R,17S,18S)-17-ethyl-10-hydroxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2,4,6,8-tetraene-1-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.4
Gsk 4 400 Rule True
Molecular Formula C21H26N2O3
Scaffold Graph Node Bond Level c1ccc2c(c1)N=C1C2CCN2CC3CCC2C1C3
Inchi Key PEBWIYPIKTWOBT-VKOMNXFXSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 3.0
Synonyms coronaridine hydroxyindolenine, coronaridine-hydroxyindolenine
Esol Class Soluble
Functional Groups CN(C)C, CO, COC(C)=O, cN=C(C)C
Compound Name methyl (1S,10S,15R,17S,18S)-17-ethyl-10-hydroxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2,4,6,8-tetraene-1-carboxylate
Exact Mass 354.194
Formal Charge 0.0
Monoisotopic Mass 354.194
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 354.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H26N2O3/c1-3-14-10-13-11-20(19(24)26-2)17(14)23(12-13)9-8-21(25)15-6-4-5-7-16(15)22-18(20)21/h4-7,13-14,17,25H,3,8-12H2,1-2H3/t13-,14+,17+,20+,21+/m1/s1
Smiles CC[C@H]1C[C@@H]2C[C@@]3([C@H]1N(C2)CC[C@]4(C3=NC5=CC=CC=C54)O)C(=O)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids