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methyl (1'S,2R,7'R,8'R,9'R)-9'-[(1S)-1-hydroxyethyl]-5-methoxy-3-oxospiro[1H-indole-2,6'-3-azatricyclo[5.3.1.03,8]undecane]-7'-carboxylate

PubChem CID: 101281058

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 88.1
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1C2CCCCC2CC12CCC1CC3CCC1C2C3
Np Classifier Class Amarylidaceae alkaloids, Iboga type
Deep Smiles COC=O)[C@]C[C@H]CN[C@@H]6[C@@H]C6)[C@@H]O)C))))CC[C@@]8NccC5=O))cccc6))OC
Heavy Atom Count 29.0
Classyfire Class Quinolizidines
Scaffold Graph Node Level OC1C2CCCCC2NC12CCN1CC3CCC1C2C3
Isotope Atom Count 0.0
Molecular Complexity 715.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name methyl (1'S,2R,7'R,8'R,9'R)-9'-[(1S)-1-hydroxyethyl]-5-methoxy-3-oxospiro[1H-indole-2,6'-3-azatricyclo[5.3.1.03,8]undecane]-7'-carboxylate
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 1.8
Gsk 4 400 Rule False
Molecular Formula C22H28N2O5
Scaffold Graph Node Bond Level O=C1c2ccccc2NC12CCN1CC3CCC1C2C3
Inchi Key QTZPBQMTXNEKRX-UZZXJJOXSA-N
Silicos It Class Soluble
Rotatable Bond Count 4.0
Synonyms montanine
Esol Class Soluble
Functional Groups CN(C)C, CO, COC(C)=O, cC(C)=O, cNC, cOC
Compound Name methyl (1'S,2R,7'R,8'R,9'R)-9'-[(1S)-1-hydroxyethyl]-5-methoxy-3-oxospiro[1H-indole-2,6'-3-azatricyclo[5.3.1.03,8]undecane]-7'-carboxylate
Exact Mass 400.2
Formal Charge 0.0
Monoisotopic Mass 400.2
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 400.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C22H28N2O5/c1-12(25)15-8-13-10-21(20(27)29-3)18(15)24(11-13)7-6-22(21)19(26)16-9-14(28-2)4-5-17(16)23-22/h4-5,9,12-13,15,18,23,25H,6-8,10-11H2,1-3H3/t12-,13-,15-,18+,21-,22-/m0/s1
Smiles C[C@@H]([C@@H]1C[C@H]2C[C@]3([C@@H]1N(C2)CC[C@]34C(=O)C5=C(N4)C=CC(=C5)OC)C(=O)OC)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids, Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Baliospermum Solanifolium (Plant) Rel Props:Reference:ISBN:9788185042145
  • 2. Outgoing r'ship FOUND_IN to/from Scadoxus Multiflorus (Plant) Rel Props:Reference:ISBN:9788185042053; ISBN:9788185042145