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Pachyrrhizin

PubChem CID: 101277

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Compound Synonyms Pachyrrhizin, Neorautone, 10091-01-7, Pachyrhizin, 6-(6-methoxy-1,3-benzodioxol-5-yl)furo[3,2-g]chromen-7-one, 3F597EPM0S, 7H-Furo(3,2-g)(1)benzopyran-7-one, 6-(6-methoxy-1,3-benzodioxol-5-yl)-, NSC-404570, 6-(6-Methoxy-1,3-benzodioxol-5-yl)-7H-furo(3,2-g)(1)benzopyran-7-one, 6-(2-Methoxy-4,5-methylenedioxyphenyl)-7H-furo[3,2-g][1]benzopyran-7-one, 7H-Furo[3,2-g][1]benzopyran-7-one, 6-(6-methoxy-1,3-benzodioxol-5-yl)-, pachyrrizine, NSC404570, NSC 404570, Spectrum_001845, SpecPlus_000199, Spectrum2_000410, Spectrum3_000875, Spectrum4_000715, Spectrum5_000921, UNII-3F597EPM0S, BSPBio_002549, KBioGR_001269, KBioSS_002355, SPECTRUM201602, DivK1c_006295, SPBio_000340, CHEMBL479689, SCHEMBL12062103, KBio1_001239, KBio2_002352, KBio2_004920, KBio2_007488, KBio3_002049, DTXSID10143573, PACHYRRHIZIN (PACHYRHIZUS), CHEBI:108580, HMS1923A15, CCG-38676, LMPK12160013, SDCCGMLS-0066383.P001, NCGC00095223-01, NCGC00095223-02, NCGC00095223-03, NCGC00095223-04, NCGC00178606-01, SR-05000002599, 6-(2-Methoxy-4,5-methylenedioxyphenyl)furocoumarin, SR-05000002599-1, 7H-Furo[3, 6-(6-methoxy-1,3-benzodioxol-5-yl)-, BRD-K02070226-001-02-0, BRD-K02070226-001-03-8, Q27187505, 6-(6-methoxy-1,3-benzodioxol-5-yl)-7-furo[3,2-g][1]benzopyranone, 6-(6-Methoxy-1,3-benzodioxol-5-yl)-7H-furo[3,2-g][1]benzopyran-7-one, 9CI, 5-BENZOFURANACRYLIC ACID, 6-HYDROXY-.ALPHA.-(2-METHOXY-4,5-(METHYLENEDIOXY)PHENYL)-, .DELTA.-LACTONE
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 67.1
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CC3CCCC3CC2CC1C1CCC2CCCC2C1
Np Classifier Class Furocoumarins, Simple coumarins
Deep Smiles COcccOCOc5cc9cccccccoc5cc9oc%13=O
Heavy Atom Count 25.0
Classyfire Class Isoflavonoids
Description Constituent of Pachyrrhizus erosus (yam bean). Pachyrrhizin is found in jicama and pulses.
Scaffold Graph Node Level OC1OC2CC3OCCC3CC2CC1C1CCC2OCOC2C1
Classyfire Subclass Isoflav-3-enes
Isotope Atom Count 0.0
Molecular Complexity 574.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id Q99714, P55210, P02791, P29466, P08684, Q9UBT6, O94782, Q9NPD5, Q9Y6L6, n.a.
Iupac Name 6-(6-methoxy-1,3-benzodioxol-5-yl)furo[3,2-g]chromen-7-one
Prediction Hob 1.0
Class Isoflavonoids
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Target Id NPT149, NPT1226, NPT277, NPT109
Xlogp 3.7
Superclass Phenylpropanoids and polyketides
Subclass Furanoisoflavonoids
Gsk 4 400 Rule True
Molecular Formula C19H12O6
Scaffold Graph Node Bond Level O=c1oc2cc3occc3cc2cc1-c1ccc2c(c1)OCO2
Prediction Swissadme 0.0
Inchi Key PENSQRMNZZWMGV-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Fcsp3 0.1052631578947368
Logs -6.86
Rotatable Bond Count 2.0
State Solid
Logd 3.309
Synonyms 6-(2-Methoxy-4,5-methylenedioxyphenyl)furocoumarin, 6-(6-Methoxy-1,3-benzodioxol-5-yl)-7H-furo[3,2-g][1]benzopyran-7-one, 9CI, Neorautone, Pachyrhizin, 6-(6-Methoxy-1,3-benzodioxol-5-yl)-7H-furo[3,2-g][1]benzopyran-7-one, 9ci, pachyrhizin
Substituent Name Furanoisoflavonoid skeleton, Linear furanocoumarin, Furanocoumarin, Isoflav-3-enone skeleton, Psoralen, Coumarin, 1-benzopyran, Benzopyran, Benzofuran, Benzodioxole, Anisole, Pyranone, Alkyl aryl ether, Benzenoid, Pyran, Heteroaromatic compound, Furan, Lactone, Oxacycle, Organoheterocyclic compound, Ether, Acetal, Hydrocarbon derivative, Organooxygen compound, Aromatic heteropolycyclic compound
Esol Class Moderately soluble
Functional Groups c1cOCO1, c=O, cOC, coc
Compound Name Pachyrrhizin
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 336.063
Formal Charge 0.0
Monoisotopic Mass 336.063
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 336.3
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Esol -3.9808538
Inchi InChI=1S/C19H12O6/c1-21-16-8-18-17(23-9-24-18)6-12(16)13-5-11-4-10-2-3-22-14(10)7-15(11)25-19(13)20/h2-8H,9H2,1H3
Smiles COC1=CC2=C(C=C1C3=CC4=C(C=C5C(=C4)C=CO5)OC3=O)OCO2
Nring 5.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Isoflav-3-enones
Np Classifier Superclass Coumarins

  • 1. Outgoing r'ship FOUND_IN to/from Agastache Rugosus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Begonia Glabra (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Neorautanenia Mitis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Oxytropis Kansuensis (Plant) Rel Props:Reference:ISBN:9788185042145
  • 5. Outgoing r'ship FOUND_IN to/from Pachyrhizus Erosus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Pachyrrhizus Erosus (Plant) Rel Props:Source_db:fooddb_chem_all;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Pogostemon Cablin (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Solanum Pubescens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all