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Grossamide

PubChem CID: 101262727

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Compound Synonyms GROSSAMIDE, 80510-06-1, UNII-63RFK5Z1GK, 63RFK5Z1GK, (+/-)-Grossamide, 3-Benzofurancarboxamide, 2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-N-(2-(4-hydroxyphenyl)ethyl)-5-((1E)-3-((2-(4-hydroxyphenyl)ethyl)amino)-3-oxo-1-propenyl)-7-methoxy-, (2R,3R)-rel-, NSC 359837, NSC-359837, CHEBI:190028, DTXSID401318494, (2S,3S)-2-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-5-[(E)-3-[2-(4-hydroxyphenyl)ethylamino]-3-oxoprop-1-enyl]-7-methoxy-2,3-dihydro-1-benzofuran-3-carboxamide, HY-N3979, AKOS040761806, (2R,3R)-2-(4-Hydroxy-3-methoxyphenyl)-N-(2-(4-hydroxyphenyl)ethyl)-5-((1E)-3-((2-(4-hydroxyphenyl)ethyl)amino)-3-oxoprop-1-en-1-yl)-7-methoxy-2,3-dihydro-1-benzofuran-3-carboxamide, DA-63902, CS-0024557, Q21547068, (2S,3S)-2-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-5-[(E)-3-[2-(4-hydroxyphenyl)ethylamino]-3-oxoprop-1-enyl]-7-methoxy-2,3-dihydro-1-benzouran-3-carboxamide, 3-BENZOFURANCARBOXAMIDE, 2,3-DIHYDRO-2-(4-HYDROXY-3-METHOXYPHENYL)-N-(2-(4-HYDROXYPHENYL)ETHYL)-5-((1E)-3-((2-(4-HYDROXYPHENYL)ETHYL)AMINO)-3-OXO-1-PROPEN-1-YL)-7-METHOXY-, (2R,3R)-REL-
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 147.0
Hydrogen Bond Donor Count 5.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CCCC1CCCCC1)CCC1CCC2CC(C3CCCCC3)C(C(C)CCCC3CCCCC3)C2C1
Np Classifier Class Neolignans
Deep Smiles COccc/C=C/C=O)NCCcccccc6))O)))))))))))ccc6O[C@@H][C@H]5C=O)NCCcccccc6))O))))))))))cccccc6)OC)))O
Heavy Atom Count 46.0
Classyfire Class 2-arylbenzofuran flavonoids
Scaffold Graph Node Level OC(CCC1CCC2OC(C3CCCCC3)C(C(O)NCCC3CCCCC3)C2C1)NCCC1CCCCC1
Isotope Atom Count 0.0
Molecular Complexity 994.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name (2S,3S)-2-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-5-[(E)-3-[2-(4-hydroxyphenyl)ethylamino]-3-oxoprop-1-enyl]-7-methoxy-2,3-dihydro-1-benzofuran-3-carboxamide
Veber Rule False
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 4.9
Gsk 4 400 Rule False
Molecular Formula C36H36N2O8
Scaffold Graph Node Bond Level O=C(C=Cc1ccc2c(c1)C(C(=O)NCCc1ccccc1)C(c1ccccc1)O2)NCCc1ccccc1
Inchi Key DROXVBRNXCRUHP-XALRPAEYSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 12.0
Synonyms grossamide
Esol Class Poorly soluble
Functional Groups CNC(C)=O, c/C=C/C(=O)NC, cO, cOC
Compound Name Grossamide
Exact Mass 624.247
Formal Charge 0.0
Monoisotopic Mass 624.247
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 624.7
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C36H36N2O8/c1-44-30-21-25(8-13-29(30)41)34-33(36(43)38-18-16-23-5-11-27(40)12-6-23)28-19-24(20-31(45-2)35(28)46-34)7-14-32(42)37-17-15-22-3-9-26(39)10-4-22/h3-14,19-21,33-34,39-41H,15-18H2,1-2H3,(H,37,42)(H,38,43)/b14-7+/t33-,34+/m0/s1
Smiles COC1=CC(=CC2=C1O[C@@H]([C@H]2C(=O)NCCC3=CC=C(C=C3)O)C4=CC(=C(C=C4)O)OC)/C=C/C(=O)NCCC5=CC=C(C=C5)O
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 1.0
Egan Rule False
Np Classifier Superclass Lignans

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