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(1S,2R,4S,5R,10S,14S,17R)-5-[(2R)-2-hydroxy-1-methylsulfinylpropan-2-yl]-10,14-dimethyl-3,6,16-trioxapentacyclo[8.6.1.02,4.04,9.014,17]heptadeca-8,12-diene-7,15-dione

PubChem CID: 101235519

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 122.0
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCC23CC2C2CC(C)C4CCCC(C42)C3C1
Np Classifier Class Nagilactone diterpenoids
Deep Smiles CS=O)C[C@@][C@H]OC=O)C=C[C@@]6O[C@@H]3[C@H]OC=O)[C@@][C@H]5[C@]%10C)CC=C6)))))C)))))))))))))O)C
Heavy Atom Count 28.0
Classyfire Class Naphthopyrans
Scaffold Graph Node Level OC1CC2C3CCCC4C(O)OC(C43)C3OC23CO1
Isotope Atom Count 0.0
Molecular Complexity 895.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 8.0
Iupac Name (1S,2R,4S,5R,10S,14S,17R)-5-[(2R)-2-hydroxy-1-methylsulfinylpropan-2-yl]-10,14-dimethyl-3,6,16-trioxapentacyclo[8.6.1.02,4.04,9.014,17]heptadeca-8,12-diene-7,15-dione
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp -0.4
Gsk 4 400 Rule False
Molecular Formula C20H24O7S
Scaffold Graph Node Bond Level O=C1C=C2C3CC=CC4C(=O)OC(C43)C3OC23CO1
Inchi Key JBOCKXJDIJBMIP-ATUGAVKGSA-N
Silicos It Class Soluble
Rotatable Bond Count 3.0
Synonyms podolactone d
Esol Class Very soluble
Functional Groups CC1=CC(=O)OC[C@]12O[C@@H]2C, CC=CC, CO, COC(C)=O, CS(C)=O
Compound Name (1S,2R,4S,5R,10S,14S,17R)-5-[(2R)-2-hydroxy-1-methylsulfinylpropan-2-yl]-10,14-dimethyl-3,6,16-trioxapentacyclo[8.6.1.02,4.04,9.014,17]heptadeca-8,12-diene-7,15-dione
Exact Mass 408.124
Formal Charge 0.0
Monoisotopic Mass 408.124
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 408.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C20H24O7S/c1-17-6-5-7-18(2)13(17)12(26-16(18)22)14-20(27-14)10(17)8-11(21)25-15(20)19(3,23)9-28(4)24/h5,7-8,12-15,23H,6,9H2,1-4H3/t12-,13+,14+,15+,17+,18-,19-,20-,28?/m0/s1
Smiles C[C@]12CC=C[C@]3([C@@H]1[C@@H]([C@@H]4[C@]5(C2=CC(=O)O[C@@H]5[C@](C)(CS(=O)C)O)O4)OC3=O)C
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Diterpenoids