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(4S,7aR,12bS,13S)-7,9-dimethoxy-3-methyl-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-13-ol

PubChem CID: 100999616

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 51.2
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3CCCC45C(CCCC34)CC(C1)C25
Np Classifier Class Isoquinoline alkaloids, Morphinan alkaloids
Deep Smiles COC=CC=C[C@][C@H]6Occ5c[C@@H][C@H]9NCC%11))C)))O))ccc6OC
Heavy Atom Count 24.0
Classyfire Class Morphinans
Scaffold Graph Node Level C1CC2CC3NCCC45C(CCCC34)OC(C1)C25
Isotope Atom Count 0.0
Molecular Complexity 616.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name (4S,7aR,12bS,13S)-7,9-dimethoxy-3-methyl-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-13-ol
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.1
Gsk 4 400 Rule True
Molecular Formula C19H21NO4
Scaffold Graph Node Bond Level C1=CC2Oc3cccc4c3C23CCNC(C4)C3=C1
Inchi Key VECPGQUFCGCGNG-CAMMJAKZSA-N
Silicos It Class Soluble
Rotatable Bond Count 2.0
Synonyms 16-hydroxythebaine
Esol Class Soluble
Functional Groups CN(C)C, CO, COC1=CC=C(C)CC1, cOC
Compound Name (4S,7aR,12bS,13S)-7,9-dimethoxy-3-methyl-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-13-ol
Exact Mass 327.147
Formal Charge 0.0
Monoisotopic Mass 327.147
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 327.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C19H21NO4/c1-20-9-8-19-11-5-7-13(23-3)18(19)24-17-12(22-2)6-4-10(14(17)19)16(21)15(11)20/h4-7,15-16,18,21H,8-9H2,1-3H3/t15-,16-,18-,19-/m0/s1
Smiles CN1CC[C@]23[C@@H]4C(=CC=C2[C@H]1[C@H](C5=C3C(=C(C=C5)OC)O4)O)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Papaver Somniferum (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279