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Tuberostemonine

PubChem CID: 100781

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Compound Synonyms Tuberostemonine, 6879-01-2, Tuberstemonine, Tubero-stemonine, (1R,3S,9R,10R,11S,14S,15S,16R)-10-ethyl-14-methyl-3-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]-12-oxa-4-azatetracyclo[7.6.1.04,16.011,15]hexadecan-13-one, CHEBI:69383, NSC 366235, Stenine, 2-(tetrahydro-4-methyl-5-oxo-2-furanyl)-, (2beta(2S,4S))-, (2S,31R,7AR,8R,8aS,11S,11aS,11bR)-8-Ethyl-11-methyl-2-((2S,4S)-4-methyl-5-oxotetrahydrofuran-2-yl)dodecahydroazepino[3,2,1-hi]furo[3,2-e]indol-10(2H)-one, Furo[2,3-h]pyrrolo[3,2,1-jk][1]benzazepin-10(2H)-one, 8-ethyldodecahydro-11-methyl-2-[(2S,4S)-tetrahydro-4-methyl-5-oxo-2-furanyl]-, (2S,7aR,8R,8aS,11S,11aS,11bR,11cR)-, (1R,3S,9R,10R,11S,14S,15S,16R)-10-ethyl-14-methyl-3-((2S,4S)-4-methyl-5-oxooxolan-2-yl)-12-oxa-4-azatetracyclo(7.6.1.04,16.011,15)hexadecan-13-one, Furo(2,3-h)pyrrolo(3,2,1-jk)(1)benzazepin-10(2H)-one, 8-ethyldodecahydro-11-methyl-2-((2S,4S)-tetrahydro-4-methyl-5-oxo-2-furanyl)-, (2S,7aR,8R,8aS,11S,11aS,11bR,11cR)-, TimTec1_001671, CHEMBL517375, SCHEMBL19197310, HMS1538L21, HY-N0352, MFCD11111456, s9056, AKOS030632869, CCG-268357, FT73792, NCGC00017300-02, AC-34126, BS-17448, 1ST169129, CS-0008906, Q27137722
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 55.8
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC(C2CC3C4CC(C)CC4CC4CCCCC2C43)C1
Np Classifier Class Stemona alkaloids
Deep Smiles CC[C@@H][C@H]CCCCN[C@H]7[C@@H][C@@H][C@H]%11OC=O)[C@H]5C))))))C[C@H]5[C@@H]C[C@@H]C=O)O5))C
Heavy Atom Count 27.0
Classyfire Class Stemona alkaloids
Scaffold Graph Node Level OC1CC2C(CC3CCCCN4C(C5CCC(O)O5)CC2C34)O1
Classyfire Subclass Stemoamide-type alkaloids
Isotope Atom Count 0.0
Molecular Complexity 636.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 10.0
Iupac Name (1R,3S,9R,10R,11S,14S,15S,16R)-10-ethyl-14-methyl-3-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]-12-oxa-4-azatetracyclo[7.6.1.04,16.011,15]hexadecan-13-one
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 3.9
Gsk 4 400 Rule True
Molecular Formula C22H33NO4
Scaffold Graph Node Bond Level O=C1CC2C(CC3CCCCN4C(C5CCC(=O)O5)CC2C34)O1
Prediction Swissadme 1.0
Inchi Key GYOGHROCTSEKDY-JJDZUBOLSA-N
Silicos It Class Soluble
Fcsp3 0.9090909090909092
Logs -4.029
Rotatable Bond Count 2.0
Logd 4.391
Synonyms tuberostemonine
Esol Class Moderately soluble
Functional Groups CN(C)C, COC(C)=O
Compound Name Tuberostemonine
Prediction Hob Swissadme 0.0
Exact Mass 375.241
Formal Charge 0.0
Monoisotopic Mass 375.241
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 375.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 10.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.4994054000000006
Inchi InChI=1S/C22H33NO4/c1-4-13-14-7-5-6-8-23-16(17-9-11(2)21(24)26-17)10-15(19(14)23)18-12(3)22(25)27-20(13)18/h11-20H,4-10H2,1-3H3/t11-,12-,13+,14+,15+,16-,17-,18+,19+,20-/m0/s1
Smiles CC[C@@H]1[C@H]2CCCCN3[C@H]2[C@H](C[C@H]3[C@@H]4C[C@@H](C(=O)O4)C)[C@@H]5[C@H]1OC(=O)[C@H]5C
Nring 5.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Ornithine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Stemona Collinsae (Plant) Rel Props:Source_db:npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Stemona Japonica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Stemona Sessilifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Stemona Tuberosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all