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Stemmadenine

PubChem CID: 10066724

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Compound Synonyms Stemmadenine, 15beta-stemmadenine, 15-beta-stemmadenine, CHEMBL486212, SCHEMBL22919364, CHEBI:142656, Q21099582, methyl (1R,2S,16E)-16-ethylidene-2-(hydroxymethyl)-4,14-diazatetracyclo[12.2.2.03,11.05,10]octadeca-3(11),5,7,9-tetraene-2-carboxylate, methyl (5E,6R,7S)-5-ethylidene-7-(hydroxymethyl)-1,4,5,6,7,8-hexahydro-2H-3,6-ethanoazonino[5,4-b]indole-7-carboxylate
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 65.6
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CCC1CC1CC3CCCCC3C1CC2
Np Classifier Class Aspidosperma type, Corynanthe type
Deep Smiles C/C=C/CNCCcc[C@@][C@@H]/9CC9)))CO))C=O)OC))))[nH]cc5cccc6
Heavy Atom Count 26.0
Classyfire Class Strychnos alkaloids
Scaffold Graph Node Level CC1CN2CCC1CC1NC3CCCCC3C1CC2
Isotope Atom Count 0.0
Molecular Complexity 578.0
Database Name imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name methyl (1R,2S,16E)-16-ethylidene-2-(hydroxymethyl)-4,14-diazatetracyclo[12.2.2.03,11.05,10]octadeca-3(11),5,7,9-tetraene-2-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.8
Gsk 4 400 Rule True
Molecular Formula C21H26N2O3
Scaffold Graph Node Bond Level C=C1CN2CCc3c([nH]c4ccccc34)CC1CC2
Inchi Key MBXJCHZRHROMQA-YVDMJPQFSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 3.0
Synonyms stemmadenine
Esol Class Soluble
Functional Groups C/C=C(/C)C, CN(C)C, CO, COC(C)=O, c[nH]c
Compound Name Stemmadenine
Exact Mass 354.194
Formal Charge 0.0
Monoisotopic Mass 354.194
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 354.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H26N2O3/c1-3-14-12-23-10-8-16-15-6-4-5-7-18(15)22-19(16)21(13-24,20(25)26-2)17(14)9-11-23/h3-7,17,22,24H,8-13H2,1-2H3/b14-3-/t17-,21+/m1/s1
Smiles C/C=C\1/CN2CC[C@H]1[C@](C3=C(CC2)C4=CC=CC=C4N3)(CO)C(=O)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

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