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(+)-Tephropurpurin

PubChem CID: 10047971

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Compound Synonyms (+)-Tephropurpurin, [(+)-5'',5''-dimethyl-4''alpha-acacetoxytetrahydrofurano(2'',3''-b)-dihydrofurano(4',5'-h)-2'-methoxy-6'-hydroxychalcone], TEPHROPURPURIN, CHEMBL457943, LMPK12120211
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 91.3
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CCC1CCCCC1)C1CCC2CC3CCCC3C2C1
Np Classifier Class Chalcones
Deep Smiles COcccO[C@@H][C@H]c5cc9C=O)/C=C/cccccc6))))))))))O)))[C@H]CO5)C)C))OC=O)C
Heavy Atom Count 31.0
Classyfire Class Linear 1,3-diarylpropanoids
Scaffold Graph Node Level OC(CCC1CCCCC1)C1CCC2OC3OCCC3C2C1
Classyfire Subclass Chalcones and dihydrochalcones
Isotope Atom Count 0.0
Molecular Complexity 711.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 3.0
Uniprot Id P47199, n.a.
Iupac Name [(1R,3aS,8bR)-8-hydroxy-6-methoxy-2,2-dimethyl-7-[(E)-3-phenylprop-2-enoyl]-3a,8b-dihydro-1H-furo[2,3-b][1]benzofuran-1-yl] acetate
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 4.0
Gsk 4 400 Rule False
Molecular Formula C24H24O7
Scaffold Graph Node Bond Level O=C(C=Cc1ccccc1)c1ccc2c(c1)C1CCOC1O2
Prediction Swissadme 1.0
Inchi Key BICKLHZENLKHGI-LXEULODHSA-N
Silicos It Class Moderately soluble
Fcsp3 0.3333333333333333
Logs -4.856
Rotatable Bond Count 6.0
Logd 2.913
Synonyms (+) tephropurpurin
Esol Class Moderately soluble
Functional Groups CC(=O)OC, c/C=C/C(c)=O, cO, cOC, cO[C@H](C)OC
Compound Name (+)-Tephropurpurin
Prediction Hob Swissadme 1.0
Exact Mass 424.152
Formal Charge 0.0
Monoisotopic Mass 424.152
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 424.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Esol -4.894635412903226
Inchi InChI=1S/C24H24O7/c1-13(25)29-22-20-19-17(30-23(20)31-24(22,2)3)12-16(28-4)18(21(19)27)15(26)11-10-14-8-6-5-7-9-14/h5-12,20,22-23,27H,1-4H3/b11-10+/t20-,22-,23+/m1/s1
Smiles CC(=O)O[C@@H]1[C@@H]2[C@@H](OC3=CC(=C(C(=C23)O)C(=O)/C=C/C4=CC=CC=C4)OC)OC1(C)C
Nring 4.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Flavonoids

  • 1. Outgoing r'ship FOUND_IN to/from Indigofera Spicata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Tephrosia Purpurea (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all