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1,2-Didemethylcolchicine

PubChem CID: 100174

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Compound Synonyms 1,2-Didemethylcolchicine, 78231-83-1, NSC354975, Acetamide, N-(5,6,7,9-tetrahydro-1,2-dihydroxy-3,10-dimethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-, CHEMBL1975605, QCOIAAVYXNEUDX-UHFFFAOYSA-N, NSC 354975, NSC-354975, Acetamide, N-(5,6,7,9-tetrahydro-1,2-dihydroxy-3,10-dimethoxy-9-oxobenzo(a)heptalen-7-yl)-,(S)-, Acetamide,6,7,9-tetrahydro-1,2-dihydroxy-3,10-dimethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-, N-(1,2-Dihydroxy-3,10-dimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide #
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 105.0
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCCC2C(CCCC3CCCCC32)C1
Np Classifier Class Phenethylisoquinoline alkaloids
Deep Smiles COcccc-ccCCCc7cc%12=O))))NC=O)C))))))cccc6O))O))OC
Heavy Atom Count 27.0
Classyfire Class Tropones
Scaffold Graph Node Level OC1CCCC2C(CCCC3CCCCC32)C1
Isotope Atom Count 0.0
Molecular Complexity 709.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name N-(1,2-dihydroxy-3,10-dimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide
Veber Rule True
Classyfire Superclass Hydrocarbon derivatives
Xlogp 0.2
Gsk 4 400 Rule True
Molecular Formula C20H21NO6
Scaffold Graph Node Bond Level O=c1cccc2c(c1)CCCc1ccccc1-2
Inchi Key QCOIAAVYXNEUDX-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 3.0
Synonyms 1,2-didemethyl colchicine, 1,2-didemethylcolchicine
Esol Class Soluble
Functional Groups CNC(C)=O, c=O, cO, cOC
Compound Name 1,2-Didemethylcolchicine
Exact Mass 371.137
Formal Charge 0.0
Monoisotopic Mass 371.137
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 371.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C20H21NO6/c1-10(22)21-14-6-4-11-8-17(27-3)19(24)20(25)18(11)12-5-7-16(26-2)15(23)9-13(12)14/h5,7-9,14,24-25H,4,6H2,1-3H3,(H,21,22)
Smiles CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)O)O)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Gloriosa Superba (Plant) Rel Props:Reference:ISBN:9788172362140