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Vasavaleha

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StorageStore in a cool place in tightly closed containers; protected from light and moisture.
Physico ChemicalLoss on drying: Not more than 12.16 per cent; Appendix 2.2.10. Total Ash: Not more than 2.5 per cent; Appendix 2.2.3. Acid-insoluble ash: Not more than 0.15 per cent; Appendix 2.2.4. Alcohol-soluble extractive: Not less than 20 per cent; Appendix 2.2.7. Water-soluble extractive: Not less than 60 per cent; Appendix 2.2.8. Total sugar: 83 to 88 per cent; Appendix 5.1.3.2. Reducing sugars: 44 to 45 per cent; Appendix 5.1.3.1. Non-reducing sugars: 38 to 43 per cent; Appendix 5.1.3.3. pH (10% aqueous solution): 4.35 to 4.9; Appendix 3.3. Assay: The formulation contains not less than 0.2 per cent of vasicine and not less than 0.2 per cent of piperine when assayed by the following methods. Estimation of vasicine: Dissolve 2 mg of vasicine in 25 ml of methanol in a volumetric flask. From this stock solution pipette out aliquots of 2 to 6 ml and make up the volume to 5 ml in volumetric flasks with methanol. Apply 10 nl of each standard solution (corresponding to 320 to 960 ng of vasicine) on TLC plate. Develop the plate to a distance of 8 cm using ethyl acetate : methanol : ammonia (8 : 2 : 0.2) as mobile phase. After development; dry the plate and scan in TLC scanner at a wavelength of 298 nm. Note the peak area under the curve for a peak corresponding to vasicine and prepare the calibration curve by plotting peak area vs amount of vasicine. Extract accurately weighed about 5 g of Vasavaleha in methanol (25 ml x 5). Filter the extract; pool; concentrate and adjust the volume to 25 ml. Apply 10 nl of test solution on TLC plate and develop; dry and scan the plate as described in the preceeding paragraph for calibration curve of vasicine. Calculate the amount of vasicine in the test solution from the calibration curve of vasicine. Estimation of piperine: Dissolve 5 mg of piperine in 100 ml of methanol. From this stock solution; pipette out 0.8 to 4.8 ml aliquots into 10 ml volumetric flasks and make up the volume with methanol to prepare standard solutions of 4 to 24 ng / ml. Apply 10 nl of each standard solution (corresponding to 40 to 240 ng) on TLC plate and develop the plate to a distance of 8 cm using dichloromethane : ethyl acetate (7.5 : 1) as mobile phase. After development; dry the plate and scan in TLC scanner at a wavelength of 337 nm. Note the peak area under the curve for a peak corresponding to piperine and prepare the calibration curve by plotting peak area vs amount of piperine. Extract accurately weighed about 5 g of Vasavaleha with ethyl acetate (25 ml x 5). Filter the extract; pool; concentrate and adjust the volume to 25 ml in a volumetric flask. Apply 10 nl of test solution on TLC plate and develop; dry and scan the plate as described in the preceding paragraph for calibration curve of piperine. Calculate the amount of piperine in the test solution from the calibration curve of piperine.
DescriptionDark brown coloured; semi solid; malleable; sticky preparation with odour of ghee; taste bitter and pungent.
Other RequirementsMicrobial limits: Appendix 2.4. Aflatoxins: Appendix 2.7.
Dosage12 g daily in divided doses.
Anupana: Milk; Water.
DefinitionVasavaleha is a semisolid avaleha preparation made with the ingredients in the Formulation composition given below.
SourceAyurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India
Time Of AdministrationTwice daily; As linctus/ frequently; Before meal/ twice daily
Ingredients
Ingredient NameScientific NamePharmacopoeia RefIpni IdPartsQuantity
Vasaka (Vasa API) svarasaAdhatoda vasicaVasa(Leaf)45128-1Lf. (Fresh)768 g
Sita APISugar candyNANANA384 g
Sarpi (Goghrta API)Clarified butter from cow’s milkNANANA96 g
Pippali APIPiper longumPippali(Fruit)682031-1Fruit96 g
Madhu APIHoneyMadhu(-)NANA384 g
Duration2-3 weeks; 15 days to one month; 1 month
Formulation NameVasavaleha
MethodTake all ingredients of pharmacopoeial quality. Take fresh leaves of Vasa; wash with water. Chop the leaves to about 2.5 cm; grind into a paste and prepare vasa svarasa through puta paka vidhi (Annexure 6.1.4) Clean; dry; grind Pippali into fine powder and pass through sieve no. 85. Add powdered Sharkara to Vasa svarasa; heat mildly and filter through muslin cloth; after complete dissolution of Sharkara. Stir continuously while heating on mild fire. Concentrate the above mixture by continuous stirring on low fire. Add Ghrta and Pippali to the above mixture and mix well. Continue heating till the preparation reaches the required consistency confirmed by the formation of a soft ball that does not disperse in water and cool to room temperature. Add honey and again mix well by continuous agitation with stirrer to make a homogeneous mixture. Pack it in tightly closed containers to protect from light and moisture.
Dosage FormGranules ; Avaleha/ linctus; Avaleha
Combined DiseasesKasa, Kaphadhika Tamaka Swasa, Pratishyaya, Kasa, Shvasa, Jvara, Raktapitta, Rajayakshma, Parsvasoola, Hrtsoola .

  • 1. Outgoing r'ship ASSOCIATED_WITH to/from Neuralgia(ID:disease_node_5536) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Parsvasoola
  • 2. Outgoing r'ship ASSOCIATED_WITH to/from Angina Pectoris(ID:disease_node_1219) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Hrtsoola
  • 3. Outgoing r'ship ASSOCIATED_WITH to/from Pleurodynia, Epidemic(ID:disease_node_6138) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Parsvasoola
  • 4. Outgoing r'ship ASSOCIATED_WITH to/from Dyspnea(ID:disease_node_2678;disease_node_21184) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Shvasa
  • 5. Outgoing r'ship ASSOCIATED_WITH to/from Cough(ID:disease_node_2282;disease_node_21170) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Kasa
  • 6. Outgoing r'ship ASSOCIATED_WITH to/from Bleeding(ID:disease_node_21108) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Raktapitta
  • 7. Outgoing r'ship ASSOCIATED_WITH to/from Rhinitis(ID:disease_node_6653) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Pratishyaya
  • 8. Outgoing r'ship ASSOCIATED_WITH to/from Wasting(ID:disease_node_21463) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Rajayakshma
  • 9. Outgoing r'ship ASSOCIATED_WITH to/from Fever(ID:disease_node_3245;disease_node_21623) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Jvara
  • 10. Outgoing r'ship ASSOCIATED_WITH to/from Blood Coagulation Disorders(ID:disease_node_1621) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Raktapitta
  • 11. Outgoing r'ship ASSOCIATED_WITH to/from Tuberculoma(ID:disease_node_7585) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Rajayakshma
  • 12. Outgoing r'ship ASSOCIATED_WITH to/from Asthma(ID:disease_node_1412) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Kaphadhika Tamaka Swasa;Shvasa

  • 1. Incoming r'ship IS_INGREDIENT_IN to/from Adhatoda Vasica (Plant) Rel Props:Matched_synonym:Adhatoda vasica; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Vasa(Leaf); Quantity:768 g; Part:Lf. (Fresh)
  • 2. Incoming r'ship IS_INGREDIENT_IN to/from Coriandrum Sativum (Plant) Rel Props:Matched_synonym:Dhoney; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:384 g
  • 3. Incoming r'ship IS_INGREDIENT_IN to/from Dendrophthoe Falcata (Plant) Rel Props:Matched_synonym:Honey Suckle Mistletoe; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:384 g
  • 4. Incoming r'ship IS_INGREDIENT_IN to/from Gleditsia Triacanthos (Plant) Rel Props:Matched_synonym:Honey Locust; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:384 g
  • 5. Incoming r'ship IS_INGREDIENT_IN to/from Justicia Adhatoda (Plant) Rel Props:Matched_synonym:Adhatoda vasica; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Vasa(Leaf); Quantity:768 g; Part:Lf. (Fresh)
  • 6. Incoming r'ship IS_INGREDIENT_IN to/from Leonurus Sibiricus (Plant) Rel Props:Matched_synonym:Honeyweed; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:384 g
  • 7. Incoming r'ship IS_INGREDIENT_IN to/from Lonicera Angustifolia (Plant) Rel Props:Matched_synonym:Narrow-Leaf Honeysuckle; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:384 g
  • 8. Incoming r'ship IS_INGREDIENT_IN to/from Lonicera Hypoleuca (Plant) Rel Props:Matched_synonym:Yellow Himalayan Honeysuckle; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:384 g
  • 9. Incoming r'ship IS_INGREDIENT_IN to/from Lonicera Japonica (Plant) Rel Props:Matched_synonym:Japanese Honeysuckle; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:384 g
  • 10. Incoming r'ship IS_INGREDIENT_IN to/from Lonicera Periclymenum (Plant) Rel Props:Matched_synonym:Dutch Honeysuckle; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:384 g
  • 11. Incoming r'ship IS_INGREDIENT_IN to/from Lonicera Quinquelocularis (Plant) Rel Props:Matched_synonym:Translucent Honeysuckle; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:384 g
  • 12. Incoming r'ship IS_INGREDIENT_IN to/from Phyllanthus Reticulatus (Plant) Rel Props:Matched_synonym:Black-Honey Shrub; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:384 g
  • 13. Incoming r'ship IS_INGREDIENT_IN to/from Piper Longum (Plant) Rel Props:Matched_synonym:Piper longum; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Pippali(Fruit); Quantity:96 g; Part:Fruit
  • 14. Incoming r'ship IS_INGREDIENT_IN to/from Tecoma Capensis (Plant) Rel Props:Matched_synonym:Cape Honeysuckle; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:384 g
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