Punarnavasava
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| Storage | Store in a cool place in tightly closed amber coloured bottle; protect from light and moisture. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Physico Chemical | Total phenolic content: Not less than 0.04 per cent w/v Appendix 5.1.1 equivalent to tannic acid; Total solids: 10 to 20 per cent w/v; Appendix 3.8 Specific gravity (at 250): 1.0 to 1.1; Appendix 3.2 p H: 3.5 to 4.5; Appendix 3.3 Reducing sugars: 7.5 to 12.5 per cent w/v; Appendix 5.1.3 Non-reducing sugars : Not more than 1.0 per cent w/v; Appendix 5.1.3 Alcohol content: 5 to 10 per cent v/v; Appendix 3.17 Methanol: Absent; Appendix 2.8 Assay: The formulation contains 0.01 to 0.02 per cent w/v of berberine; when assayed by the following method: Estimation of berberine: Apply 1.0 to 8.0 nl of (5 data point) berberine solution prepared under thin layer chromatography on TLC plate and develop the plate to a distance of 8 cm using n-butanol: ethyl acetate: formic acid : water (3 : 5 : 1 : 1) as mobile phase. After development allow the plate to dry in a current of cold air and scan in the TLC scanner at a wavelength of 366 nm. Note the peak areas under curve for the peak corresponding to berberine and prepare the calibration curve by plotting peak area vs. concentration of berberine. Process vacuum-dried 400 ml of the formulation under thin layer chromatography. Apply 1 nl of the test solution on TLC plate. Develop; dry and scan the plate for calibration curve of berberine. Calculate the amount of berberine in the test solution from the calibration curve of berberine. Other Requirements: Microbial load: Appendix 2.4 Aflatoxins: Appendix 2.7 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Description | Clear dark brown liquid without frothing and significant sedimentation; with aromatic odour and acrid taste | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Dosage | 15 - 30 ml orally with equal amount of water after meals twice a day. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Anupana | Equal quantity of water | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Definition | Punarnavasava is a fermented liquid preparation; made with the ingredients of the Formulation composition given below. It contains not more than 10 per cent; and not less than 5 per cent of alcohol that is self generated in the preparation over a period of time. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Source | Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Time Of Administration | After meal/twice daily | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Ingredients |
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| Duration | 2-3 weeks | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Formulation Name | Punarnavasava | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Method | Take the raw materials of pharmacopoeial quality. Wash; dry and powder the ingredients numbered 1 to 20 of the formulation composition individually and pass through the sieve number 44 to obtain coarse powder. Wash and clean the ingredient number 22 of the formulation composition. Add specified amount of water to the ingredient number 23 of the formulation composition; allow to dissolve and filter through the muslin cloth. Transfer the filtrate to a clean container; add Madhu; Draksa; Dhataka and coarsely powdered other drugs. Seal the mouth of the container. Shift the container to the fermentation room and constantly check for the signs of completion of fermentation process. Filter the fermented material through a clean muslin cloth. Pack in air tight containers and allow for maturation. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Dosage Form | Asava | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Combined Diseases | Pandu, Shotha, Udararoga, Pl aha, Amlapitta, Yakrit, Gulma, Jvara, Kricchrasadhya Roga . |
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ASSOCIATED_WITHto/from Inflammation(ID:disease_node_4305;disease_node_21103) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Shotha - 3. Outgoing r'ship
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ASSOCIATED_WITHto/from Abdominal Lump(ID:disease_node_21488) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Gulma - 7. Outgoing r'ship
ASSOCIATED_WITHto/from Fever(ID:disease_node_3245;disease_node_21623) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Jvara - 8. Outgoing r'ship
ASSOCIATED_WITHto/from Anemia(ID:disease_node_1179) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Pandu
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IS_INGREDIENT_INto/from Adhatoda Vasica (Plant) Rel Props:Matched_synonym:Adhatoda vasica; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Vasa(Leaf); Quantity:16 g; Part:Root - 2. Incoming r'ship
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IS_INGREDIENT_INto/from Berberis Aristata (Plant) Rel Props:Matched_synonym:Berberis aristata; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Daruharidra(Stem); Quantity:16 g; Part:Stem - 5. Incoming r'ship
IS_INGREDIENT_INto/from Boerhaavia Diffusa (Plant) Rel Props:Matched_synonym:Boerhaavia diffusa; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Raktapunarnava(Root); Quantity:16 g; Part:Root - 6. Incoming r'ship
IS_INGREDIENT_INto/from Boerhavia Diffusa (Plant) Rel Props:Matched_synonym:Boerhaavia diffusa; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Raktapunarnava(Root); Quantity:16 g; Part:Root - 7. Incoming r'ship
IS_INGREDIENT_INto/from Coriandrum Sativum (Plant) Rel Props:Matched_synonym:Dhoney; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:800 g - 8. Incoming r'ship
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IS_INGREDIENT_INto/from Fagonia Cretica (Plant) Rel Props:Matched_synonym:Fagonia cretica; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Dhanvayasa(Whole plant); Quantity:16 g; Part:Root - 10. Incoming r'ship
IS_INGREDIENT_INto/from Gleditsia Triacanthos (Plant) Rel Props:Matched_synonym:Honey Locust; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:800 g - 11. Incoming r'ship
IS_INGREDIENT_INto/from Justicia Adhatoda (Plant) Rel Props:Matched_synonym:Adhatoda vasica; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Vasa(Leaf); Quantity:16 g; Part:Root - 12. Incoming r'ship
IS_INGREDIENT_INto/from Leonurus Sibiricus (Plant) Rel Props:Matched_synonym:Honeyweed; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:800 g - 13. Incoming r'ship
IS_INGREDIENT_INto/from Lonicera Angustifolia (Plant) Rel Props:Matched_synonym:Narrow-Leaf Honeysuckle; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:800 g - 14. Incoming r'ship
IS_INGREDIENT_INto/from Lonicera Hypoleuca (Plant) Rel Props:Matched_synonym:Yellow Himalayan Honeysuckle; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:800 g - 15. Incoming r'ship
IS_INGREDIENT_INto/from Lonicera Japonica (Plant) Rel Props:Matched_synonym:Japanese Honeysuckle; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:800 g - 16. Incoming r'ship
IS_INGREDIENT_INto/from Lonicera Periclymenum (Plant) Rel Props:Matched_synonym:Dutch Honeysuckle; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:800 g - 17. Incoming r'ship
IS_INGREDIENT_INto/from Lonicera Quinquelocularis (Plant) Rel Props:Matched_synonym:Translucent Honeysuckle; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:800 g - 18. Incoming r'ship
IS_INGREDIENT_INto/from Phyllanthus Reticulatus (Plant) Rel Props:Matched_synonym:Black-Honey Shrub; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:800 g - 19. Incoming r'ship
IS_INGREDIENT_INto/from Picrorhiza Kurroa (Plant) Rel Props:Matched_synonym:Picrorhiza kurroa; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Katuka(Rhizome); Quantity:16 g; Part:Rt./Rz. - 20. Incoming r'ship
IS_INGREDIENT_INto/from Piper Longum (Plant) Rel Props:Matched_synonym:Piper longum; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Pippali(Fruit); Quantity:16 g; Part:Fruit - 21. Incoming r'ship
IS_INGREDIENT_INto/from Piper Nigrum (Plant) Rel Props:Matched_synonym:Piper nigrum; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Marica(Fruit); Quantity:16 g; Part:Fruit - 22. Incoming r'ship
IS_INGREDIENT_INto/from Raphanus Raphanistrum (Plant) Rel Props:Matched_synonym:Raphanus sativus; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Mulaka(Root); Quantity:16 g; Part:Root - 23. Incoming r'ship
IS_INGREDIENT_INto/from Raphanus Sativus (Plant) Rel Props:Matched_synonym:Raphanus sativus; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Mulaka(Root); Quantity:16 g; Part:Root - 24. Incoming r'ship
IS_INGREDIENT_INto/from Ricinus Communis (Plant) Rel Props:Matched_synonym:Ricinus communis; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Eranda(Root); Quantity:16 g; Part:Root - 25. Incoming r'ship
IS_INGREDIENT_INto/from Saccharum Officinarum (Plant) Rel Props:Matched_synonym:Sugarcane; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Sarkara(-); Quantity:1.6 kg - 26. Incoming r'ship
IS_INGREDIENT_INto/from Scindapsus Officinalis (Plant) Rel Props:Matched_synonym:Scindapsus officinalis; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Gajapippali(Fruit); Quantity:16 g; Part:Fruit - 27. Incoming r'ship
IS_INGREDIENT_INto/from Solanum Indicum (Plant) Rel Props:Matched_synonym:Solanum indicum; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Brhati(Root); Quantity:16 g; Part:Root - 28. Incoming r'ship
IS_INGREDIENT_INto/from Solanum Surattense (Plant) Rel Props:Matched_synonym:Solanum surattense; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Kantakari(Whole plant); Quantity:16 g; Part:Whole plant - 29. Incoming r'ship
IS_INGREDIENT_INto/from Tecoma Capensis (Plant) Rel Props:Matched_synonym:Cape Honeysuckle; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Quantity:800 g - 30. Incoming r'ship
IS_INGREDIENT_INto/from Terminalia Bellirica (Plant) Rel Props:Matched_synonym:Terminalia bellirica; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Bibhitaka(Fruit); Quantity:16 g; Part:Fr.P - 31. Incoming r'ship
IS_INGREDIENT_INto/from Terminalia Chebula (Plant) Rel Props:Matched_synonym:Terminalia chebula; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Haritaki(Fruit); Quantity:16 g; Part:Fr.P - 32. Incoming r'ship
IS_INGREDIENT_INto/from Tinospora Cordifolia (Plant) Rel Props:Matched_synonym:Tinospora cordifolia; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Guduci(Stem); Quantity:16 g; Part:Stem - 33. Incoming r'ship
IS_INGREDIENT_INto/from Tinospora Sinensis (Plant) Rel Props:Matched_synonym:Tinospora cordifolia; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Guduci(Stem); Quantity:16 g; Part:Stem - 34. Incoming r'ship
IS_INGREDIENT_INto/from Tribulus Terrestris (Plant) Rel Props:Matched_synonym:Tribulus terrestris; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Goksura(Fruit); Quantity:16 g; Part:Fruit - 35. Incoming r'ship
IS_INGREDIENT_INto/from Trichosanthes Dioica (Plant) Rel Props:Matched_synonym:Trichosanthes dioica; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Quantity:16 g; Part:Leaf - 36. Incoming r'ship
IS_INGREDIENT_INto/from Vitis Vinifera (Plant) Rel Props:Matched_synonym:Vitis vinifera; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Draksa(Fruit); Quantity:320 g; Part:Dr. Fr. - 37. Incoming r'ship
IS_INGREDIENT_INto/from Woodfordia Fruticosa (Plant) Rel Props:Matched_synonym:Woodfordia fruticosa; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Dhataki(Flower); Quantity:256 g; Part:Flower - 38. Incoming r'ship
IS_INGREDIENT_INto/from Zingiber Officinale (Plant) Rel Props:Matched_synonym:Zingiber officinale; Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India; Match_type:synonym_exact; Pharmacopoeia_ref:Sunthi(Rhizome); Quantity:16 g; Part:Rhizome