Punarnavadi Mandura

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Plants (Ingredients) :

Diseases (Associated With) :

Phytochemicals :

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Storage

Store in a cool place in tightly closed containers; protect from light and moisture.

Definition

Punarnavadi Mandura (Tablet) is a compressed tablet preparation made with the ingredients in the Formulation Composition given below.

Ingredients

Ingredient Name	Scientific Name	Pharmacopoeia Ref	Ipni Id	Parts	Quantity
Punarnava (Rakta Punarnava API)	Boerhaavia diffusa	Raktapunarnava(Root)	326899-2	Root	48 g
Trivrit API	Ipomea turpethum	NA	269996-1	Root	48 g
Vyosa	NA	NA	NA	NA	NA
Shuntha API	Zingiber officinale	Sunthi(Rhizome)	798372-1	Rhizome	48 g
Marica API	Piper nigrum	Marica(Fruit)	682369-1	Fruit	48 g
Pippala API	Piper longum	Pippali(Fruit)	682031-1	Fruit	48 g
Vidanga API	Embelia ribes	Vidanga(Fruit)	588451-1	Fruit	48 g
Daru (Devadaru API)	Cedrus deodara	Devadaru(Heart wood)	676701-1	Heart wood	48 g
Citraka API	Plumbago zeylanica	Citraka(Root)	687109-1	Root	48 g
Kustha API	Saussurea lappa	Kustha(Root)	242389-1	Root	48 g
Haridradvaya	NA	NA	NA	NA	NA
Haridra API	Curcuma longa	Haridra(Rhizome)	796451-1	Rhizome	48 g
Daruharidra API	Berberis aristata	Daruharidra(Stem)	106428-1	Stem	48 g
Triphala	NA	NA	NA	NA	NA
Harataka API	Terminalia chebula	Haritaki(Fruit)	171037-1	Pericarp	48 g
Amalaka API	Emblica officinalis	Amalaki(Fresh fruit)	345266-1	Pericarp	48 g
Bibhataka API	Terminalia bellirica	Bibhitaka(Fruit)	170982-1	Pericarp	48 g
Danta API	Baliospermum montanum	Danti(Root)	339718-1	Root	48 g
Cavya API	Piper chaba	NA	680861-1	Stem	48 g
Kalingaka (Indrayava API)	Holarrhena antidysenterica	Indrayava(Seed)	79291-1	Seed	48 g
Pippala API	Piper longum	Pippali(Fruit)	682031-1	Fruit	48 g
Pippalamula (Pippala API)	Piper longum	Pippalimula(Stem)	682031-1	Stem	48 g
Musta (Musta API)	Cyperus rotundus	Musta(Rhizome)	305797-1	Rhizome	48 g
Mandura (Mandura Bhasma (API))	Calcined Mandura	NA	NA	NA	1.920 kg
Gomutra (API)	Cow urine	NA	NA	NA	6.144 l

Source

Ayurvedic Pharmacopeia of India

Physico Chemical

Total ash: Not more than 60 per cent; Appendix 2.2.3 Acid-insoluble ash: Not more than 28 per cent; Appendix 2.2.4 Methanol-soluble extractive: 15 to17 per cent; Appendix 2.2.7 Water-soluble extractive: 24 to 26 per cent; Appendix 2.2.8 Loss on drying: Not more than 8 per cent; Appendix 2.2.10 pH (10% aqueous solution): 6 to 7 Appendix 3.3 Disintegration time Not more than 20 min Appendix 3.18 Average weight 250 (+5) mg Appendix 3.19 Assay: Total Iron: Not less than 14 per cent w/w Appendix 5.6 Other Requirements: Microbial limits: Complies with Appendix 2.4 Aflotoxins : Complies with Appendix 2.6

Description

Reddish brown coloured tablet with the characteristic odour of Gomutra Identifications: Thin layer chromatography: Extract 2 g of formulation with 20 ml of alcohol for 400 for about 3 h. Filter and concentrate the extract to 5 ml and carry out thin layer chromatography. Apply 10 nl of extract on TLC plate and develop the plate to a distance of 8 cm using toluene: ethyl acetate: acetic acid (5: 4.5: 0.5) as mobile phase. After development; allow the plate to dry in air. Spray the plate with anisaldehyde sulphuric acide reagent followed by heating at 1050 for about 10 min. The plate shows spots at Rf 0.30 (light blue); 0.66 (yellow); 0.70 (green) and 0.76; 0.85 (both blue).

Dosage

1 to 2 g per day in divided doses

Formulation Name

Punarnavadi Mandura

Anupana

Buttermilk; water

Method

 Take all the ingredients of pharmacopoeial quality.  Treat Mandura to prepare Mandura bhasma.  Wash; clean; dry the ingredients numbered 1 to 15 of the formulation composition; powder separately and pass through 180 nm I. S. sieve(sieve number 85) to obtain fine powder and mix them all to a homogeneous mixture.  Strain Gomutra through muslin cloth.  Add Gomutra to Mandura bhasma; heat in a stainless steel container stirring continuously and observe the mixture for formation of a thick paste.  Stop the heating and allow to cool to 500.  Add mixture of fine powders and mix thoroughly to prepare a homogeneous lumpy mass (dough). Allow to cool.  Pass the dough through a granulator to obtain granules and add 0.5 per cent of talc powder as lubricant. Subject the granules to compression in a tablet punching machine.  Store tablets in containers and pack them air-tight to protect from light and moisture.

1. Incoming r'ship IS_INGREDIENT_IN to/from Baliospermum Montanum (Plant) Rel Props:Matched_synonym:Baliospermum montanum; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Danti(Root); Quantity:48 g; Part:Root
2. Incoming r'ship IS_INGREDIENT_IN to/from Baliospermum Solanifolium (Plant) Rel Props:Matched_synonym:Baliospermum montanum; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Danti(Root); Quantity:48 g; Part:Root
3. Incoming r'ship IS_INGREDIENT_IN to/from Berberis Aristata (Plant) Rel Props:Matched_synonym:Berberis aristata; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Daruharidra(Stem); Quantity:48 g; Part:Stem
4. Incoming r'ship IS_INGREDIENT_IN to/from Boerhaavia Diffusa (Plant) Rel Props:Matched_synonym:Boerhaavia diffusa; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Raktapunarnava(Root); Quantity:48 g; Part:Root
5. Incoming r'ship IS_INGREDIENT_IN to/from Boerhavia Diffusa (Plant) Rel Props:Matched_synonym:Boerhaavia diffusa; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Raktapunarnava(Root); Quantity:48 g; Part:Root
6. Incoming r'ship IS_INGREDIENT_IN to/from Cedrus Deodara (Plant) Rel Props:Matched_synonym:Cedrus deodara; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Devadaru(Heart wood); Quantity:48 g; Part:Heart wood
7. Incoming r'ship IS_INGREDIENT_IN to/from Curcuma Longa (Plant) Rel Props:Matched_synonym:Curcuma longa; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Haridra(Rhizome); Quantity:48 g; Part:Rhizome
8. Incoming r'ship IS_INGREDIENT_IN to/from Cyperus Rotundus (Plant) Rel Props:Matched_synonym:Cyperus rotundus; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Musta(Rhizome); Quantity:48 g; Part:Rhizome
9. Incoming r'ship IS_INGREDIENT_IN to/from Embelia Ribes (Plant) Rel Props:Matched_synonym:Embelia ribes; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Vidanga(Fruit); Quantity:48 g; Part:Fruit
10. Incoming r'ship IS_INGREDIENT_IN to/from Holarrhena Antidysenterica (Plant) Rel Props:Matched_synonym:Holarrhena antidysenterica; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Indrayava(Seed); Quantity:48 g; Part:Seed
11. Incoming r'ship IS_INGREDIENT_IN to/from Holarrhena Pubescens (Plant) Rel Props:Matched_synonym:Holarrhena antidysenterica; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Indrayava(Seed); Quantity:48 g; Part:Seed
12. Incoming r'ship IS_INGREDIENT_IN to/from Phyllanthus Emblica (Plant) Rel Props:Matched_synonym:Emblica officinalis; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Amalaki(Fresh fruit); Quantity:48 g; Part:Pericarp
13. Incoming r'ship IS_INGREDIENT_IN to/from Piper Chaba (Plant) Rel Props:Matched_synonym:Piper chaba; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Quantity:48 g; Part:Stem
14. Incoming r'ship IS_INGREDIENT_IN to/from Piper Longum (Plant) Rel Props:Matched_synonym:Piper longum; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Pippalimula(Stem); Quantity:48 g; Part:Stem
15. Incoming r'ship IS_INGREDIENT_IN to/from Piper Nigrum (Plant) Rel Props:Matched_synonym:Piper nigrum; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Marica(Fruit); Quantity:48 g; Part:Fruit
16. Incoming r'ship IS_INGREDIENT_IN to/from Piper Retrofractum (Plant) Rel Props:Matched_synonym:Piper chaba; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Quantity:48 g; Part:Stem
17. Incoming r'ship IS_INGREDIENT_IN to/from Plumbago Zeylanica (Plant) Rel Props:Matched_synonym:Plumbago zeylanica; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Citraka(Root); Quantity:48 g; Part:Root
18. Incoming r'ship IS_INGREDIENT_IN to/from Saussurea Costus (Plant) Rel Props:Matched_synonym:Saussurea lappa; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Kustha(Root); Quantity:48 g; Part:Root
19. Incoming r'ship IS_INGREDIENT_IN to/from Saussurea Lappa (Plant) Rel Props:Matched_synonym:Saussurea lappa; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Kustha(Root); Quantity:48 g; Part:Root
20. Incoming r'ship IS_INGREDIENT_IN to/from Terminalia Bellirica (Plant) Rel Props:Matched_synonym:Terminalia bellirica; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Bibhitaka(Fruit); Quantity:48 g; Part:Pericarp
21. Incoming r'ship IS_INGREDIENT_IN to/from Terminalia Chebula (Plant) Rel Props:Matched_synonym:Terminalia chebula; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Haritaki(Fruit); Quantity:48 g; Part:Pericarp
22. Incoming r'ship IS_INGREDIENT_IN to/from Zingiber Officinale (Plant) Rel Props:Matched_synonym:Zingiber officinale; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Sunthi(Rhizome); Quantity:48 g; Part:Rhizome

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Punarnavadi Mandura

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Formulation Properties

Associated Connections 22

Plant Connections 22