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Mrdvikadi lehya

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StorageStore in a cool place in tightly closed containers; protected from light and moisture.
DefinitionMrdvikadi Leha is a semisolid avaleha preparation made with the ingredients in the Formulation composition given below.
Ingredients
Ingredient NameScientific NamePharmacopoeia RefIpni IdPartsQuantity
Mrdvika (Draksha API)Vitis viniferaDraksa(Fruit)30478388-2Dr. Fr.50 in number
Pippali APIPiper longumPippali(Fruit)682031-1Fruit30 in number
Sharkara APISugarSarkara(-)NANA48 g
Madhu APIHoneyMadhu(-)NAQ.S.NA
Physico ChemicalTotal Ash: Not more than 1.0 per cent; Appendix 2.2.3. Acid-insoluble ash: Not more than 0.2 per cent; Appendix 2.2.4. Alcohol-soluble extractive: Not less than 30.0 per cent; Appendix 2.2.7. Water-soluble extractive: Not less than 90.0 per cent; Appendix 2.2.8. Total tannins: 0.4 to 0.56 per cent; Appendix 5.1.2. Total phenolics: 0.7 to 0.8 per cent; Appendix 5.1.1. Total sugar: 70 to 73 per cent; Appendix 5.1.3.2. Reducing sugars: 50 to 51 per cent; Appendix 5.1.3.1. Non-reducing sugars: 20 to 23 per cent; Appendix 5.1.3.3. pH (5% aqueous solution): 4.0 to 4.3; Appendix 3.3. Assay: The formulation contains not less than 2.0 per cent gallic acid when assayed by the following method. Estimation of gallic acid: Dissolve 10 mg of gallic acid in 100 ml of methanol in a volumetric flask. From this stock solution; prepare standard solutions of 15 to 75 ng / ml by transferring aliquots (1.5 to 7.5 ml) of stock solution to 10 ml volumetric flasks and adjusting the volume to 10 ml with methanol. Apply 10 nl each of standard solution corresponding to 150 ng to 750 ng of gallic acid on a TLC plate and develop the plate to a distance of 8 cm using toluene : ethyl acetate : formic acid : methanol (3 : 3 : 0.8 : 0.2 ) as mobile phase. After development; dry the plate and scan in TLC scanner at a wavelength of 337 nm. Note the area under the curve for a peak corresponding to gallic acid and prepare the calibration curve by plotting peak area vs amount of gallic acid. Hydrolyze accurately weighed about 5 g avaleha by refluxing with 50 ml of 2N hydrochloric acid on a water-bath. Filter; add equal amount of water; transfer to a separating funnel and extract with diethyl ether (20 ml x 4). Collect the diethyl ether layer and dry. Dissolve the residue in methanol and make up the volume to 25 ml in a volumetric flask. Apply 10 nl on TLC plate and develop; dry and scan the plate as described in the preceding paragraph for calibration curve of gallic acid. Note area under the curve for a peak corresponding to gallic acid in each track of test solution. Calculate the amount of gallic acid in the test solution from the calibration curve of gallic acid.
SourceAyurvedic Pharmacopeia of India
DescriptionDark brown coloured; semi solid; malleable; sticky preparation with a pungent; slightly sweet and sour taste.
Other RequirementsMicrobial Limits: Appendix 2.4. Aflatoxins: Appendix 2.7.
Dosage25 g daily in divided doses.
Formulation NameMrdvikadi lehya
Anupana: Water; Milk.
MethodTake all ingredients of pharmacopoeial quality. Wash the Mrdvika two or three times with fresh water; till it becomes clean; and drain the water completely. Remove the seeds and crush to a fine paste. Powder dried Pippali and Sharkara separately and pass through sieve No. 85. Triturate all the ingredients of the composition to a homogeneous mixture by adding required amount of Madhu; to form a semisolid mass. Pack it in tightly closed containers to protect from light and moisture.
Combined DiseasesKasa .

  • 1. Incoming r'ship IS_INGREDIENT_IN to/from Annona Squamosa (Plant) Rel Props:Matched_synonym:Sugar Apple; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_contains; Pharmacopoeia_ref:Sarkara(-); Quantity:48 g
  • 2. Incoming r'ship IS_INGREDIENT_IN to/from Coriandrum Sativum (Plant) Rel Props:Matched_synonym:Dhoney; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Part:Q.S.
  • 3. Incoming r'ship IS_INGREDIENT_IN to/from Dendrophthoe Falcata (Plant) Rel Props:Matched_synonym:Honey Suckle Mistletoe; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Part:Q.S.
  • 4. Incoming r'ship IS_INGREDIENT_IN to/from Gleditsia Triacanthos (Plant) Rel Props:Matched_synonym:Honey Locust; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Part:Q.S.
  • 5. Incoming r'ship IS_INGREDIENT_IN to/from Leonurus Sibiricus (Plant) Rel Props:Matched_synonym:Honeyweed; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Part:Q.S.
  • 6. Incoming r'ship IS_INGREDIENT_IN to/from Lonicera Angustifolia (Plant) Rel Props:Matched_synonym:Narrow-Leaf Honeysuckle; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Part:Q.S.
  • 7. Incoming r'ship IS_INGREDIENT_IN to/from Lonicera Hypoleuca (Plant) Rel Props:Matched_synonym:Yellow Himalayan Honeysuckle; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Part:Q.S.
  • 8. Incoming r'ship IS_INGREDIENT_IN to/from Lonicera Japonica (Plant) Rel Props:Matched_synonym:Japanese Honeysuckle; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Part:Q.S.
  • 9. Incoming r'ship IS_INGREDIENT_IN to/from Lonicera Periclymenum (Plant) Rel Props:Matched_synonym:Dutch Honeysuckle; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Part:Q.S.
  • 10. Incoming r'ship IS_INGREDIENT_IN to/from Lonicera Quinquelocularis (Plant) Rel Props:Matched_synonym:Translucent Honeysuckle; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Part:Q.S.
  • 11. Incoming r'ship IS_INGREDIENT_IN to/from Phyllanthus Reticulatus (Plant) Rel Props:Matched_synonym:Black-Honey Shrub; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Part:Q.S.
  • 12. Incoming r'ship IS_INGREDIENT_IN to/from Piper Longum (Plant) Rel Props:Matched_synonym:Piper longum; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Pippali(Fruit); Quantity:30 in number; Part:Fruit
  • 13. Incoming r'ship IS_INGREDIENT_IN to/from Saccharum Officinarum (Plant) Rel Props:Matched_synonym:Sugarcane; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_contains; Pharmacopoeia_ref:Sarkara(-); Quantity:48 g
  • 14. Incoming r'ship IS_INGREDIENT_IN to/from Tecoma Capensis (Plant) Rel Props:Matched_synonym:Cape Honeysuckle; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_contains; Pharmacopoeia_ref:Madhu(-); Part:Q.S.
  • 15. Incoming r'ship IS_INGREDIENT_IN to/from Vitis Vinifera (Plant) Rel Props:Matched_synonym:Vitis vinifera; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Draksa(Fruit); Quantity:50 in number; Part:Dr. Fr.
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