Kakamaci Arka
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| Storage | Store in a cool place in tightly closed containers; protected from light and moisture. | ||||||||||||||||||
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| Definition | Kakamaca Arka is a liquid preparation obtained by hydro-distillation of fruits of Solanum nigrum. | ||||||||||||||||||
| Ingredients |
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| Physico Chemical | Specific gravity (200): 0.998 to 1.0; Appendix 3.2 | ||||||||||||||||||
| Source | Ayurvedic Pharmacopeia of India | ||||||||||||||||||
| Description | Kakamaca Arka is a light greenish liquid with slight turbidity; taste slightly bitter. Identification Thin layer chromatography: Dissolve 0.1 ml of the oil obtained by hydro-distillation of the Arka in 1 ml of toluene. In a separate setup extract Kakamaca oil from Kakamaca API and dissolve 0.1 ml of oil in 1 ml of toluene or in any suitable solvent. Apply 2 nl each of the solution of oils on TLC plate separately and develop the plate to a distance of 8 cm using toluene: ethyl acetate (97: 3) as mobile phase. After development; allow the plate to dry in air and spray the plate with acetic anhydride sulphuric acid reagent followed by heating at 1050 for about 10 min. Both the chromatograms show major spots at Rf 0.17 (yellowish Grey) and 0.63 (sky blue) in visible light. Gas Chromatography: Carry out Gas chromatography using a 30 m fused silica capillary column walls coated with BP- 10 maintained at 1500 for 2 min programmed at the rate of 70/min to 2000 again 150/17 min to 2600 and detector at 3000 and with a flow rate of carrier gas 1.5 ml/ min with injection port temperature 2600. Inject separately 0.1nl each of the oil obtained by hydro-distillation of the crude drug as well as of the Arka and programme the column as given above. Both the chromatograms show major peaks at Rt 22.01; 23.53 and 23.75. | ||||||||||||||||||
| Other Requirements | Microbial limits: Complies with Appendix 2.4 Aflatoxins: Complies with Appendix 2.6 | ||||||||||||||||||
| Dosage | 10 to 20 ml per day in divided doses | ||||||||||||||||||
| Formulation Name | Kakamaci Arka | ||||||||||||||||||
| Method | Take the raw materials of pharmacopoeial quality. Wash; dry and powder the ingredient number 1 of the Formulation Composition and pass through the 355 nm I. S. sieve (sieve number 44) to obtain coarse powder. Place 100 g of Kakamaca powder in a round bottom standard joint flask of 5.0 l capacity. Add 3.0 l of Jala. Attach the proper distillation assembly; double surface condenser and receiving flask and enough circulating water to condense the distillate i.e. Arka. Place the flask on a heating mantle. Adjust the temperature control when boiling starts control and continue the distillation to collect about 2 1 of Arka. Store in containers and pack them air-tight to protect from light and moisture. | ||||||||||||||||||
| Combined Diseases | Hrid roga, Yakridroga, Shotha |
- 1. Outgoing r'ship
ASSOCIATED_WITHto/from Liver Diseases(ID:disease_node_4822) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Yakridroga - 2. Outgoing r'ship
ASSOCIATED_WITHto/from Inflammation(ID:disease_node_4305;disease_node_21103) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Shotha
- 1. Incoming r'ship
IS_INGREDIENT_INto/from Solanum Americanum (Plant) Rel Props:Matched_synonym:Solanum nigrum; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Kakamaci(Whole plant); Quantity:1.0 kg; Part:Fruit - 2. Incoming r'ship
IS_INGREDIENT_INto/from Solanum Nigrum (Plant) Rel Props:Matched_synonym:Solanum nigrum; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Kakamaci(Whole plant); Quantity:1.0 kg; Part:Fruit