Gutika Maricadi Gutika
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| Storage | Store in a cool place in tightly closed containers; protected from light and moisture. | ||||||||||||||||||||||||||||||||||||
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| Definition | Maricadi Gutika is a preparation made with the i ngredients in the Formulation composition given below. | ||||||||||||||||||||||||||||||||||||
| Ingredients |
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| Physico Chemical | Loss on drying at 110 0: Not more than 10 per cent; Appendix 2.2.10. Total ash: Not more than 6 per cent; Appendix 2.2.3. Acid-insoluble ash: Not more than 1 per cent; Appendix 2.2.4. Alcohol-soluble extractive: Not less than 9 per cent; Appendix 2.2.7. Water-soluble extractive: Not less than 46 per cent; Appendix 2.2.8. Assay: Not less than 2.83 per cent of piperine when assayed by the following method. Estimation of Piperine: Dissolve 2.5 mg of piperine in a mixture of methanol : chloroform (1 : 1) and make up the volume to 25 ml in a volumetric flask. Apply 2; 5; 8; 11; 14; 17 nl of solution on TLC plate and develop the plate a distance of to 8 cm using acetone : n-hexane (3 : 7) as mobile phase. After development; dry the plate in a current of hot air and scan in the TLC scanner at a wavelength of 338 nm. Note the peak area and prepare the calibration curve by plotting peak area vs concentration of piperine. Extract accurately weighed about 6 g powder of vatis in 100 ml of alcohol in a Soxhlet apparatus for 6 h. Filter the extract while hot and dry completely and weigh. Take 25 mg of extract in a volumetric flask and dissolve in a mixture of methanol : chloroform (1 : 1) and make up the volume to 25 ml. Apply 3 nl of the test solutions on TLC plate. Develop; dry and scan the plate as described in the proceeding paragraph for calibration curve of piperine. Record area under the curve for a peak corresponding to piperine in the test solution. Calculate the amount of piperine in the test solution from the calibration curve of piperine. | ||||||||||||||||||||||||||||||||||||
| Source | Ayurvedic Pharmacopeia of India | ||||||||||||||||||||||||||||||||||||
| Description | Ksara are alkaline substances obtained from the water soluble ash of the drugs of plant origin. | ||||||||||||||||||||||||||||||||||||
| Other Requirements | Microbial Limits: Appendix 2.4. Aflatoxins: Appendix 2.7. | ||||||||||||||||||||||||||||||||||||
| Dosage | 3 g per day – to be dissolved slowly in the mouth. | ||||||||||||||||||||||||||||||||||||
| Formulation Name | Gutika Maricadi Gutika | ||||||||||||||||||||||||||||||||||||
| Method | Take all ingredients of Pharmacopoeial quality. Clean; dry; powder the ingredients no. 1; 2 & 4 of the formulation composition (Prak¾ epa Dravya) and pass through sieve number 85 to obtain fine powder. Collect Yava ksara in the specified ratio. Take jaggery; add required amounts of water; boil to dissolve and filter through a muslin cloth. Reduce to thicker consistency by gentle boiling to prepare Gu² a pāka. Add fine powders of Prak¾epa Dravya and Yava k¾āra and mix thoroughly to prepare a homogeneous mass. Pass the mass through a pill making machine and cut vatis of desirable weight. Roll the vatis on a flat surface by circular motion of palm. Dry the rolled vatis in a tray-dryer at a temperature not exceeding 600. Pack it in tightly closed containers to protect from light and moisture. | ||||||||||||||||||||||||||||||||||||
| Combined Diseases | Kasa, Shvasa . |
- 1. Outgoing r'ship
ASSOCIATED_WITHto/from Asthma(ID:disease_node_1412) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Shvasa - 2. Outgoing r'ship
ASSOCIATED_WITHto/from Dyspnea(ID:disease_node_2678;disease_node_21184) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Shvasa - 3. Outgoing r'ship
ASSOCIATED_WITHto/from Cough(ID:disease_node_2282;disease_node_21170) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Kasa
- 1. Incoming r'ship
IS_INGREDIENT_INto/from Hordeum Vulgare (Plant) Rel Props:Matched_synonym:Hordeum vulgare; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Yava(Fruit); Quantity:6g; Part:Water soluble ash of plant - 2. Incoming r'ship
IS_INGREDIENT_INto/from Piper Longum (Plant) Rel Props:Matched_synonym:Piper longum; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Pippali(Fruit); Quantity:12 g; Part:Fruit - 3. Incoming r'ship
IS_INGREDIENT_INto/from Piper Nigrum (Plant) Rel Props:Matched_synonym:Piper nigrum; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Marica(Fruit); Quantity:12 g; Part:Fruit - 4. Incoming r'ship
IS_INGREDIENT_INto/from Punica Granatum (Plant) Rel Props:Matched_synonym:Punica granatum; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Dadima(Fruit rind); Quantity:24 g; Part:Fruit rind