Citrakadi Gutika
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| Storage | Store in a cool place in tightly closed containers; protected from light and moisture. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Definition | Citrakadi Gutika is a pill preparation made with the ingredients in the Formulation Composition given below. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Ingredients |
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| Physico Chemical | Total Ash: Not more than 51 per cent; Appendix 2.2.3 Acid-insoluble ash: Not more than 2 per cent; Appendix 2.2.4 Alcohol-soluble extractive: Not less than 8 per cent; Appendix 2.2.7 Water-soluble extractive: Not less than 56 per cent; Appendix 2.2.8 Loss on drying: Not more than 10 per cent; Appendix 2.2.10 pH (10 % aqueous solution): 3. 5 to 4.5; Appendix 3.3 Assay: Contains not less than 0.10 per cent of piperine when assayed by the following method. Dissolve 1.0 mg of piperine in a mixture of methanol: chloroform (1: 1) and make up the volume to 10 ml in a volumetric flask. Apply 1; 2; 6; 10; 14; 18 nl of solution on TLC plate and develop the plate to 8 cm using n-hexane: acetone (7: 3) as mobile phase. After development; dry the plate in a current of hot air and scan in the TLC scanner at a wavelength of 338 nm. Note the peak area and prepare the calibration curve by plotting peak area vs concentration of piperine. Extract accurately weighed 2g powder of vati in 75 ml of alcohol in Soxhlet apparatus for 6 h. Filter the extract while hot and dry completely and weigh. Take 100 mg in volumetric flask and dissolve in a mixture of methanol-chloroform (1:1) and make up the volume to 25 ml. Apply 25 nl of the test solutions on TLC plate. Develop; dry and scan the plate as described in the proceeding paragraph for calibration curve of piperine. Record the area under the curve for a peak corresponding to piperine in the test solution. Calculate the amount of piperine in the test solution from the calibration curve of piperine. Sodium: Not less than 12.0 per cent w/w; Appendix 5.10. Potassium: Not less than 5.0 per cent w/w; Appendix 5.10. Chloride: Not less than 21.00 per cent w/w; Appendix 5.11. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Source | Ayurvedic Pharmacopeia of India | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Description | Light brown coloured pills with characteristic asafoetida odour and bitter taste | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Other Requirements | Microbial limits: Complies with Appendix 2.4 Aflatoxins: Complies with Appendix 2.6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Dosage | 500 mg - 1 g per day in divided doses with warm water/ Butter milk | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Formulation Name | Citrakadi Gutika | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Method | Take all ingredients of pharmacopoeial quality. Treat Hingu to get Hingu -Shuddha. (Appendix 6.2.8.15). Wash; clean; dry the ingredients number 1; 2; 5; 7 and 8 of the Formulation Composition; powder separately and pass through 180 nm I. S. sieve(sieve number 85). Roast coarsely powdered ingredients numbered 4 of the Formulation Composition in a stainless steel pan on low flame till free from moisture; powder separately and pass through 180 nm I. S. sieve(sieve number 85). Roast ingredient number 2 of the formulation composition in a stainless steel pan on low flame till free from moisture. ∗ Dadima (seed) rasa may also be alternatively used. Wash and clean fresh Matulunga fruits; cut into halves; squeeze and strain the juice through muslin cloth to obtain Matulunga svarasa. Mix all the ingredients thoroughly to prepare a homogenous blend. Add svarasa in required quantity and triturate well to prepare a bolus. Expel the mass through vata machine to obtain cylindrical threads and cut the vatas to a desired weight. Roll the vatas on flat surface to round them by circular motion of palm covered with a glove or use suitable mechanical device. Dry the rounded vatas in a tray-dryer at a temperature not exceeding 600 for 10 to 12 h. Store vatas in containers and pack them air-tight to protect from light and moisture. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Combined Diseases | Agnimandya, Amadosa, Grahana |
- 1. Outgoing r'ship
ASSOCIATED_WITHto/from Dyspepsia(ID:disease_node_2674) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Agnimandya - 2. Outgoing r'ship
ASSOCIATED_WITHto/from Malabsorption Syndromes(ID:disease_node_4952) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Grahana
- 1. Incoming r'ship
IS_INGREDIENT_INto/from Apium Leptophyllum (Plant) Rel Props:Matched_synonym:Apium leptophyllum; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Ajamoda(Fruit); Quantity:1 part; Part:Fruit - 2. Incoming r'ship
IS_INGREDIENT_INto/from Citrus Aurantifolia (Plant) Rel Props:Matched_synonym:Citrus aurantifolia; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Quantity:QS; Part:Fr. Juice - 3. Incoming r'ship
IS_INGREDIENT_INto/from Citrus Aurantiifolia (Plant) Rel Props:Matched_synonym:Citrus aurantifolia; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Quantity:QS; Part:Fr. Juice - 4. Incoming r'ship
IS_INGREDIENT_INto/from Cyclospermum Leptophyllum (Plant) Rel Props:Matched_synonym:Apium leptophyllum; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Ajamoda(Fruit); Quantity:1 part; Part:Fruit - 5. Incoming r'ship
IS_INGREDIENT_INto/from Ferula Foetida (Plant) Rel Props:Matched_synonym:Ferula foetida; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Hingu(Oleo-gum resin); Quantity:1 part; Part:Exudate - 6. Incoming r'ship
IS_INGREDIENT_INto/from Hordeum Vulgare (Plant) Rel Props:Matched_synonym:Hordeum vulgare; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Yava(Fruit); Quantity:1 part; Part:Water soluble ash of Pl. - 7. Incoming r'ship
IS_INGREDIENT_INto/from Piper Chaba (Plant) Rel Props:Matched_synonym:Piper chaba; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Quantity:1 part; Part:Stem - 8. Incoming r'ship
IS_INGREDIENT_INto/from Piper Longum (Plant) Rel Props:Matched_synonym:Piper longum; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Pippali(Fruit); Quantity:1 part; Part:Fruit - 9. Incoming r'ship
IS_INGREDIENT_INto/from Piper Nigrum (Plant) Rel Props:Matched_synonym:Piper nigrum; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Marica(Fruit); Quantity:1 part; Part:Fruit - 10. Incoming r'ship
IS_INGREDIENT_INto/from Piper Retrofractum (Plant) Rel Props:Matched_synonym:Piper chaba; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Quantity:1 part; Part:Stem - 11. Incoming r'ship
IS_INGREDIENT_INto/from Plumbago Zeylanica (Plant) Rel Props:Matched_synonym:Plumbago zeylanica; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Citraka(Root); Quantity:1 part; Part:Root - 12. Incoming r'ship
IS_INGREDIENT_INto/from Zingiber Officinale (Plant) Rel Props:Matched_synonym:Zingiber officinale; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Sunthi(Rhizome); Quantity:1 part; Part:Rhizome