Brahmi Arka
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| Storage | Store in a cool place in tightly closed containers; protected from light and moisture. | ||||||||||||||||||
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| Definition | Brahma Arka is a liquid preparation obtained by hydro-distillation of whole plant of Bacopa monnieri. | ||||||||||||||||||
| Ingredients |
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| Physico Chemical | Specific gravity (200): 0.998 to 1.0; Appendix 3.2 | ||||||||||||||||||
| Source | Ayurvedic Pharmacopeia of India | ||||||||||||||||||
| Description | Brahma Arka is a turbid pale yellow liquid with a faint odour and slightly astringent taste. Identification Thin layer chromatography: Dissolve 0.1 ml of the oil obtained by hydro-distillation of the Arka in 1 ml of toluene or in any suitable solvent. In a separate setup extract Brahma oil from Brahma API. Apply 2 nl each of the solutions on TLC plate separately and develop the plate to a distance of 8 cm using toluene: ethyl acetate (97: 3) as mobile phase. After development; allow the plate to dry in air and spray the plate with anisaldehyde sulphuric acid reagent followed by heating at 1050 for bout 10 min. and examine under ultraviolet light at 254 nm. Both the chromatograms show major spots at Rf 0.17 (purple brown); 0.35 (red brown) and 0.63 (saffron red). Gas Chromatography: Carry out the gas chromatography using a 30 m fused silica capillary column walls coated with BP-10 maintained at 1500 for 2 min. programmed at the rate of 70/min to 2000; again 150/17 min. to 2600 and detector at 3000 with a flow rate of carrier gas 1.5 ml/ min. with injection port temperature 2800. Inject separately 0.1nl of oil obtained by hydro-distillation of the crude drug as well as of Arka and programme the column as given in preceding paragraph. Both the chromatograms show major peaks at Rt 14.12; 20.42; 14.23 and 21.78. | ||||||||||||||||||
| Other Requirements | Microbial limits: Complies with Appendix 2.4 Aflatoxins: Complies with Appendix 2.6 | ||||||||||||||||||
| Dosage | 10 to 20 ml per day in divided doses | ||||||||||||||||||
| Formulation Name | Brahmi Arka | ||||||||||||||||||
| Method | Take the raw materials of pharmacopoeial quality. Wash; dry and powder the ingredient number 1 of the Formulation Composition and pass through the 355 nm I. S. sieve (sieve number44) to obtain coarse powder. Place 100 g of Brahma powder in a round bottom standard joint flask of 5.0 l capacity. Add 3.0 l of Jala. Attach the proper distillation assembly; double surface condenser and receiving flask and enough circulating water to condense the distillate i.e. Arka. Place the flask on a heating mantle. Adjust the temperature control when boiling starts and continue the distillation to collect about 2.0 l of Arka. Store in containers and pack them air-tight to protect from light and moisture. | ||||||||||||||||||
| Combined Diseases | Buddhimandata, Smritibhrama |
- 1. Outgoing r'ship
ASSOCIATED_WITHto/from Memory Loss(ID:disease_node_21583) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Smritibhrama - 2. Outgoing r'ship
ASSOCIATED_WITHto/from Intellectual Disability(ID:disease_node_5155;disease_node_15856) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Buddhimandata - 3. Outgoing r'ship
ASSOCIATED_WITHto/from Memory Impairment(ID:disease_node_21595) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines; Ayurvedic Pharmacopeia of India
- 1. Incoming r'ship
IS_INGREDIENT_INto/from Bacopa Monnieri (Plant) Rel Props:Matched_synonym:Bacopa monnieri; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Brahmi(Whole plant); Quantity:1.0 kg; Part:Whole plant