Babbularista
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| Storage | Store in a cool place in tightly closed amber coloured bottle; protect from light and moisture. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Definition | Babbularista is a fermented liquid preparation made with the ingredients in the Formulation composition given below. It contains not more than 10 per cent; and not less than 5 per cent of alcohol that is self generated in the preparation over a period of time. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Ingredients |
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| Physico Chemical | Total phenolic content: 0.187 to 0.208 per cent w/v Appendix 5.1.1 equivalent to tannic acid; Total solids: Not less than 16.5 per cent w/v; Appendix 3.8 Specific gravity (at 25 ): 1.05 to 1.10; Appendix 3.2 p H: 4.0 to 4.50; Appendix 3.3 Reducing sugars: Not less than 4.20 per cent w/v; Appendix 5.1.3 Non-reducing sugars: Not more than 0.80 per cent w/v; Appendix 5.1.3 Alcohol content: 5 to 10 per cent v/v; Appendix 3.17 Methanol: Absent; Appendix 2.8 Assay: The formulation contains 0.02 to 0.10 per cent w/v of gallic acid; when assayed by the following method: Estimation of gallic acid : Apply 1.0 to 8.0 nl of (5 data point) standard solution of gallic acid prepared under thin layer chromatography on TLC plate and develop the plate to a distance of 8 cm using toluene: ethyl acetate: acetic acid: methanol (3 : 3 : 0.8 : 0.2) as mobile phase. Derivatise the plate with Natural product reagent and dry in a current of cold air and scan in the TLC scanner at a wavelength of 366 nm. Record the peak area under curve for a peak corresponding to gallic acid and plot the calibration curve by plotting the peak area vs concentration of gallic acid. Dry about 50 ml; accurately measured; of the formulation in vacuum to remove the self generated alcohol. Add 30 ml methanol to dissolve the extract. Filter and dry the methanolic extract in vacuum and weigh. Dissolve about 10 mg; accurately weighed; of the residue in 1 ml of methanol taken from graduated pipette. Apply 15 nl on TLC plate and carry out thin layer chromatography. Develop; dry and scan the plate as described in preceding paragraph for calibration curve of gallic acid. Calculate the amount of gallic acid in the test solution from the calibration curve of gallic acid. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Source | Ayurvedic Pharmacopeia of India | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Description | Clear; dark brown liquid without frothing and significant sedimentation; with astringent taste | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Other Requirements | Microbial limit: Appendix 2.4 Aflatoxins: Appendix 2.7 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Dosage | 15 – 30 ml orally with equal amount of water after meals twice a day. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Formulation Name | Babbularista | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Method | Take the raw materials of pharmacopoeial quality. Wash; dry and powder the ingredient numbered 1 (Kvatha Dravya) of the formulation composition and pass through the sieve number 44 to obtain coarse powder. Clean; dry and powder the ingredients numbered 5 to 13 (Praksepa Dravya) of the formulation composition individually and pass through the sieve number 85 to obtain fine powder. Add specified amounts of water to the Kvatha Dravya; soak overnight; heat; reduce to one fourth and filter through muslin cloth to obtain Kvatha. Add the ingredient number 3 of the formulation composition to the Kvatha; allow to dissolve and filter through the muslin cloth. Transfer the filtrate to a clean container; add Dhataka and other finely powdered Praksepa Dravyas. Seal the mouth of the container. Shift the container to the fermentation room and constantly check for the signs of completion of fermentation process. Filter the fermented material through a clean muslin cloth. Pack in air tight containers and allow for maturation. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Combined Diseases | Ksaya, Kustha, Atisara, Prameha, Shvasa, Kasa . |
- 1. Outgoing r'ship
ASSOCIATED_WITHto/from Skin Diseases(ID:disease_node_6968) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Kustha - 2. Outgoing r'ship
ASSOCIATED_WITHto/from Skin Diseases, Genetic(ID:disease_node_6970) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Kustha - 3. Outgoing r'ship
ASSOCIATED_WITHto/from Tuberculosis, Pulmonary(ID:disease_node_7644) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Ksaya - 4. Outgoing r'ship
ASSOCIATED_WITHto/from Diarrhea(ID:disease_node_2504) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Atisara - 5. Outgoing r'ship
ASSOCIATED_WITHto/from Asthma(ID:disease_node_1412) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Shvasa - 6. Outgoing r'ship
ASSOCIATED_WITHto/from Dysentery(ID:disease_node_2637;disease_node_2638) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Atisara - 7. Outgoing r'ship
ASSOCIATED_WITHto/from Urinary System Symptom(ID:disease_node_21274) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Prameha - 8. Outgoing r'ship
ASSOCIATED_WITHto/from Dyspnea(ID:disease_node_2678;disease_node_21184) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Shvasa - 9. Outgoing r'ship
ASSOCIATED_WITHto/from Cough(ID:disease_node_2282;disease_node_21170) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:Kasa
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IS_INGREDIENT_INto/from Cinnamomum Zeylanicum (Plant) Rel Props:Matched_synonym:Cinnamomum zeylanicum; Source_db:Ayurvedic Pharmacopeia of India; Match_type:synonym_exact; Pharmacopoeia_ref:Tvak(Bark); Quantity:48 g; Part:Stem bark - 6. Incoming r'ship
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