Amrtarista
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| Storage | Store in a cool place in tightly closed amber coloured bottle; protect from light and moisture. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Definition | Amritarista is a fermented liquid preparation made with the ingredients in the Formulation composition given below. It contains not more than 10 per cent; and not less than 5 per cent of alcohol that is self generated in the preparation over a period of time. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Ingredients |
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| Physico Chemical | Total phenolic content: 0.080 to 0.103 per cent w/v Appendix 5.1.1 equivalent to tannic acid; Total solids: Not less than 25.0 per cent w/v; Appendix 3.8 Specific gravity (at 250): 1.05 to 1.20; Appendix 3.2 p H: 3.40 to 4.40; Appendix 3.3 Reducing sugars: Not less than 16 per cent w/v; Appendix 5.1.3 Non-reducing sugars : Not more than 0.80 per cent w/v; Appendix 5.1.3 Alcohol content : 5 to 8 per cent v/v; Appendix 3.17 Methanol: Absent; Appendix 2.8 Assay: The formulation contains 0.01 to 0.07 per cent w/v of luteolin when assayed by the following method: Estimation of luteolin: Apply separately 1.0 to 8.0 nl (5 data point) of standard solution of luteolin prepared under thin layer chromatography; on TLC plate and develop the plate to a distance of 8 cm using toluene: ethyl acetate: acetic acid (5 : 4 : 1). Derivatise the plate with Natural product reagent and dry in a current of cold air and scan in the TLC scanner at a wavelength of 366 nm. Record the peak area under curve and plot the calibration curve for the peak corresponding to luteolin by plotting the peak area vs. concentration of luteolin. Dry about 50 ml; accurately measured; of the formulation in vacuum to remove the self generated alcohol. Add 50 ml water to dissolve the extract and partition successively with n- hexane (50 ml x 3); chloroform (50 ml x 3) and ethyl acetate (50 ml x 3). Filter and concentrate the ethyl acetate extract under vacuum and weigh. Dissolve about 20 mg; accurately weighed; residue in 1 ml of methanol taken from a graduated pipette. Apply 2 nl on TLC plate and carry out thin layer chromatography. Develop; dry and scan the plate as described in preceding paragraph for calibration curve of luteolin. Calculate the amount of luteolin in the test solution from the calibration curve of luteolin. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Source | Ayurvedic Pharmacopeia of India; Ayurvedic Formulary of India | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Description | Clear; dark brown liquid without frothing and significant sedimentation; with astringent taste | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Other Requirements | Microbial limit: Appendix 2.4 Aflatoxins: Appendix 2.7 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Dosage | 15 – 30 ml orally with equal amount of water after meals twice a day. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Formulation Name | Amrtarista | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Method | Take the raw material of pharmacopoeial quality. Wash; dry and powder the ingredients numbered 1 to 11 (Kvatha Dravya) of the formulation composition individually and pass through the sieve number 44 to obtain coarse powder. Clean; dry and powder the ingredients numbered 14 to 24 (Praksepa Dravya) of the formulation composition individually and pass through the sieve number 85 to obtain fine powder. Add specified amounts of water to the Kvatha Dravya; soak overnight; heat; reduce to one fourth and filter through muslin cloth to obtain Kvatha. Add the ingredient number 13 of the formulation composition to the Kvatha; allow to dissolve and filter through the muslin cloth. Transfer the filtrate to a clean container; add the finely powdered Praksepa Dravyas and seal the mouth of the container. Shift the container to the fermentation room and constantly check for the signs of completion of fermentation process. Filter the fermented material through a clean muslin cloth. Pack in air tight containers and allow for maturation. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Combined Diseases | All types of Jvara . |
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ASSOCIATED_WITHto/from Fever(ID:disease_node_3245;disease_node_21623) (Disease) Rel Props:Source_db:Ayurvedic Standard Treatment Guidelines;Ayurvedic Pharmacopeia of India; Ayurvedic_term:All Types Of Jvara
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