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Xanthomatosis, Cerebrotendinous

Disease ID: disease_node_9912

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DbxrefGARD:5622, MESH:D019294, MIM:213700, NCI:C84628, ORDO:909, SNOMEDCT_US_2023_03_01:63246000, UMLS_CUI:C0238052
SubclassofDOID_3345
Data SourceDOID, MESH
SynonymsCholestanol storage disease
Mesh IdD019294
Mesh LabelXanthomatosis, Cerebrotendinous
Mesh SubclassofD008052, D014973
Doid Labelcerebrotendinous xanthomatosis
Doid DescriptionA xanthomatosis that is characterized by a deficiency in the production of the bile acid, chenodeoxycholic acid that has_material_basis_in homozygous or compound heterozygous mutation in the CYP27A1 gene, which encodes sterol 27-hydroxylase, on chromosome 2q35. OMIM mapping confirmed by DO. [SN].
Disease Node Iddisease_node_9912
Doid IdDOID_4810
LabelXanthomatosis, Cerebrotendinous